DNAJC10 (N-Term) Rabbit pAb
Référence MBS8553270-0,1mL-Cy5.5
Conditionnement : 0.1mL(Cy5.5)
Marque : MyBiosource
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DNAJC10 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8553270MBS8553270 is an antibody targeting DNAJC10. Also known as DNAJC10 (N-Term) Rabbit pAb. Reactive in Mouse. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
DNAJC10, Polyclonal Antibody
Full Product Name
DNAJC10 (N-Term) Rabbit pAb
Product Gene Name
anti-DNAJC10 antibody
Product Synonym Names
DnaJ homolog subfamily C member 10; 184-; Endoplasmic reticulum DNA J domain-containing protein 5; ER-resident protein ERdj5; ERdj5; Macrothioredoxin; MTHr; DNAJC10; ERDJ5
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB38590
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied in PBS with 0.09% (W/V) Sodium Azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Affinity Purified
OMIM
607987
Immunogen
This DNAJC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-82 amino acids from the N-terminal region of human DNAJC10.
Cellular Localization
Endoplasmic Reticulum
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DNAJC10 antibody
Western Blot (WB)
Application Notes for anti-DNAJC10 antibody
WB: 1:1000
Other Notes
Small volumes of anti-DNAJC10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for DNAJC10. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dnaJ homolog subfamily C member 10 isoform 2
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member C10
NCBI Official Symbol
DNAJC10
NCBI Official Synonym Symbols
JPDI; MTHr; ERdj5; PDIA19
UniProt Protein Name
DnaJ homolog subfamily C member 10
UniProt Synonym Protein Names
Endoplasmic reticulum DNA J domain-containing protein 5; ER-resident protein ERdj5; ERdj5; Macrothioredoxin
Protein Family
DnaJ homolog subfamily
UniProt Gene Name
DNAJC10
UniProt Synonym Gene Names
ERDJ5; ER-resident protein ERdj5; ERdj5; MTHr
UniProt Entry Name
DJC10_HUMAN
NCBI Protein Information
dnaJ homolog subfamily C member 10
NCBI Summary for DNAJC10
This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
Show more UniProt Comments for DNAJC10
DNAJC10: This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. May act as a co-chaperone for HSPA5. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Chaperone; Secreted, signal peptide; Secreted; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 2q32.1
Cellular Component: membrane; endoplasmic reticulum; endoplasmic reticulum lumen
Molecular Function: disulfide oxidoreductase activity; protein binding; ATPase activator activity; chaperone binding; protein disulfide oxidoreductase activity; Hsp70 protein binding; misfolded protein binding; oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; ATPase binding
Biological Process: ER-associated protein catabolic process; negative regulation of protein amino acid phosphorylation; positive regulation of ATPase activity; cell redox homeostasis
Show more Protein type: Chaperone; Secreted, signal peptide; Secreted; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 2q32.1
Cellular Component: membrane; endoplasmic reticulum; endoplasmic reticulum lumen
Molecular Function: disulfide oxidoreductase activity; protein binding; ATPase activator activity; chaperone binding; protein disulfide oxidoreductase activity; Hsp70 protein binding; misfolded protein binding; oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; ATPase binding
Biological Process: ER-associated protein catabolic process; negative regulation of protein amino acid phosphorylation; positive regulation of ATPase activity; cell redox homeostasis
Research Articles on DNAJC10
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-DNAJC10 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Protein Processing In Endoplasmic Reticulum Pathway antibodies | Protein Processing In Endoplasmic Reticulum Pathway Diagram |
| Protein Processing In Endoplasmic Reticulum Pathway antibodies | Protein Processing In Endoplasmic Reticulum Pathway Diagram |
Diseases associated with anti-DNAJC10 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >3 publications with DNAJC10 and Neoplasms |
| Adenocarcinoma Antibodies | >1 publications with DNAJC10 and Adenocarcinoma |
| Liver Neoplasms Antibodies | >1 publications with DNAJC10 and Liver Neoplasms |
| Liver Diseases Antibodies | >1 publications with DNAJC10 and Liver Diseases |
| Carcinoma, Hepatocellular Antibodies | >1 publications with DNAJC10 and Carcinoma, Hepatocellular |
Organs/Tissues associated with anti-DNAJC10 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Pancreas Antibodies | >1 publications with DNAJC10 and Pancreas |
| Embryonic Tissue Antibodies | >1 publications with DNAJC10 and Embryonic Tissue |
| Thymus Antibodies | >1 publications with DNAJC10 and Thymus |
| Mouth Antibodies | >1 publications with DNAJC10 and Mouth |
| Kidney Antibodies | >1 publications with DNAJC10 and Kidney |
| Liver Antibodies | >1 publications with DNAJC10 and Liver |
| Brain Antibodies | >1 publications with DNAJC10 and Brain |
| Testis Antibodies | >1 publications with DNAJC10 and Testis |