ERRFI1 Polyclonal Antibody Cy5 Conjugated
Référence MBS9462866-5x0,1mL
Conditionnement : 5x0.1mL
Marque : MyBiosource
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ERRFI1 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9462866MBS9462866 is an antibody targeting ERRFI1. Also known as ERRFI1 Polyclonal Antibody Cy5 Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
ERRFI1, Polyclonal Antibody
Full Product Name
ERRFI1 Polyclonal Antibody Cy5 Conjugated
Product Gene Name
anti-ERRFI1 antibody
Product Synonym Names
ERRFI1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purity/Purification
affinity purified by Protein A
Preparation and Storage
Store at -20 degree C for one year. Avoid repeated freeze/thaw cycles.
Shipped at 4 degree C.
Shipped at 4 degree C.
Applications Tested/Suitable for anti-ERRFI1 antibody
Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-ERRFI1 antibody
ICC: 1:50-200
IF: 1:50-200
IF: 1:50-200
Other Notes
Small volumes of anti-ERRFI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for ERRFI1. It may not necessarily be applicable to this product.
NCBI Official Full Name
ERBB receptor feedback inhibitor 1
NCBI Official Synonym Full Names
ERBB receptor feedback inhibitor 1
NCBI Official Symbol
ERRFI1
NCBI Official Synonym Symbols
MIG6; RALT; MIG-6; GENE-33
UniProt Protein Name
ERBB receptor feedback inhibitor 1
UniProt Synonym Protein Names
Mitogen-inducible gene 6 protein; MIG-6
Protein Family
ERBB receptor feedback inhibitor
UniProt Gene Name
ERRFI1
UniProt Synonym Gene Names
MIG6; MIG-6
UniProt Entry Name
ERRFI_HUMAN
NCBI Protein Information
ERBB receptor feedback inhibitor 1; mitogen-inducible gene 6 protein; receptor-associated late transducer
NCBI Summary for ERRFI1
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008]
Show more UniProt Comments for ERRFI1
MIG-6: Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4. Important for normal keratinocyte proliferation and differentiation. Plays a role in modulating the response to steroid hormones in the uterus. Required for normal response to progesterone in the uterus and for fertility. Mediates epithelial estrogen responses in the uterus by regulating ESR1 levels and activation. Important for regulation of endometrium cell proliferation. Important for normal prenatal and perinatal lung development. Interacts with ERBB2. Interacts with EGFR. Levels are very low in quiescent cells. Up-regulated by mitogens. Belongs to the MIG6 family.
Protein type: Tumor suppressor; Inhibitor
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: extrinsic to internal side of plasma membrane; cytoplasm; nucleus
Molecular Function: protein binding; protein kinase binding
Biological Process: negative regulation of epidermal growth factor receptor activity; skin morphogenesis; response to stress; negative regulation of protein amino acid autophosphorylation; regulation of keratinocyte differentiation; alveolus development
Show more Protein type: Tumor suppressor; Inhibitor
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: extrinsic to internal side of plasma membrane; cytoplasm; nucleus
Molecular Function: protein binding; protein kinase binding
Biological Process: negative regulation of epidermal growth factor receptor activity; skin morphogenesis; response to stress; negative regulation of protein amino acid autophosphorylation; regulation of keratinocyte differentiation; alveolus development
Research Articles on ERRFI1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-ERRFI1 antibody
| Reference Product | PubMed Publications |
|---|---|
| EGFR antibody | >19 publications with ERRFI1 and EGFR |
| ERBB2 antibody | >2 publications with ERRFI1 and ERBB2 |
| CDC42 antibody | >1 publications with ERRFI1 and CDC42 |
Pathways associated with anti-ERRFI1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| EGFR1 Signaling Pathway antibodies | EGFR1 Signaling Pathway Diagram |
| Signaling Pathways In Glioblastoma antibodies | Signaling Pathways In Glioblastoma Diagram |
Diseases associated with anti-ERRFI1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Hyperplasia Antibodies | >4 publications with ERRFI1 and Hyperplasia |
| Skin Neoplasms Antibodies | >3 publications with ERRFI1 and Skin Neoplasms |
| Liver Diseases Antibodies | >3 publications with ERRFI1 and Liver Diseases |
| Hypertrophy Antibodies | >2 publications with ERRFI1 and Hypertrophy |
| Disease Models, Animal Antibodies | >2 publications with ERRFI1 and Disease Models, Animal |
| Cardiovascular Diseases Antibodies | >2 publications with ERRFI1 and Cardiovascular Diseases |
| Liver Neoplasms Antibodies | >1 publications with ERRFI1 and Liver Neoplasms |
| Carcinoma, Hepatocellular Antibodies | >1 publications with ERRFI1 and Carcinoma, Hepatocellular |
| Weight Gain Antibodies | >1 publications with ERRFI1 and Weight Gain |
| Neoplasms, Experimental Antibodies | >1 publications with ERRFI1 and Neoplasms, Experimental |
Organs/Tissues associated with anti-ERRFI1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Uterus Antibodies | >5 publications with ERRFI1 and Uterus |
| Skin Antibodies | >5 publications with ERRFI1 and Skin |
| Blood Antibodies | >4 publications with ERRFI1 and Blood |
| Liver Antibodies | >4 publications with ERRFI1 and Liver |
| Lung Antibodies | >3 publications with ERRFI1 and Lung |
| Bone Antibodies | >2 publications with ERRFI1 and Bone |
| Pancreas Antibodies | >2 publications with ERRFI1 and Pancreas |
| Brain Antibodies | >2 publications with ERRFI1 and Brain |
| Nerve Antibodies | >1 publications with ERRFI1 and Nerve |
| Thyroid Antibodies | >1 publications with ERRFI1 and Thyroid |