FASL Antibody
Référence OACD03404-1ML
Conditionnement : 1ml
Marque : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for FASL Antibody (OACD03404) |
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| Predicted Species Reactivity | Human|Porcine|Rat|Simian |
|---|---|
| Product Format | Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | ICC|IHC|IHC-P|IP|WB |
| Reconstitution and Storage | -20°C|2°C to 8°C |
| Immunogen | Range: Gln102 - Leu280 |
| Purification | Affinity Purified; Protein A Purified |
| Concentration | 0.5 mg/ml |
| Preservative | 0.02% NaN3 |
| Specificity | The antibody is a rabbit polyclonal antibody raised against FASL. It has been selected for its ability to recognize FASL in immunohistochemical staining and western blotting. |
| Formulation | PBS, pH7.4, containing 0.02% NaN3, 50% glycerol |
| Application Data | Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5,000 Optimal working dilutions must be determined by end user. |
| Gene Symbol | FASLG |
|---|---|
| Gene Full Name | Fas ligand |
| Alias Symbols | CD95 ligand, CD95-L, CD95L, FAS antigen CD95, fas antigen ligand, FASL, TNFSF6, tumor necrosis factor ligand superfamily member 6. |
| NCBI Gene Id | 574159 |
| Protein Name | Tumor necrosis factor ligand superfamily member 6 |
| Description of Target | Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. |
| Uniprot ID | P63307 |
| Protein Accession # | NP_001028010.1 |
| Nucleotide Accession # | NM_001032838 |
| Molecular Weight | 31 kDa |
