GABA A Receptor alpha 5 (GABRA5) (NM_000810) Human Mass Spec Standard

Specifications

Product Data
Tag	C-Myc/DDK
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC216541
Predicted MW	52.1 kDa
Protein Sequence	Protein Sequence >Peptide sequence encoded by RC216541 Blue=ORF Red=Cloning site Green=Tag(s) MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLG ERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNG KKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTN GSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQ VSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFT KRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSE SKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV Recombinant protein using RC216541 also available, TP316541M
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage	Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability	Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping	Dry Ice
Reference Data
RefSeq	NP_000801
RefSeq Size	2352
RefSeq ORF	1386
Synonyms	DEE79; EIEE79
Locus ID	2558
UniProt ID	P31644
Cytogenetics	15q12
Summary	GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. provided by RefSeq, Jul 2008
Protein Families	Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

FAQs

Protein FAQs

SDS

SDS for PH316541

Recombinant Protein Resources

Video tutorial: Why protein expression host matters Webinar Video: Overexpression lysate as positive controls for Western blot Product Overview Video: Overexpression lysates as positive controls for Western blot Video Tutorial: Knockout(KO) lysate and antibody specificity Product Brochure: Protein

SKU	Description	Size
LC400284	Lyophilized GABRA5 HEK293T cell transient overexpression lysate (as WB positive control)	20 ug
LC431938	Lyophilized GABRA5 HEK293T cell transient overexpression lysate (as WB positive control)	20 ug
LY400284	Transient overexpression lysate of gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5), transcript variant 1 (as WB positive control)	100 ug
LY431938	Transient overexpression lysate of gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5), transcript variant 2 (as WB positive control)	100 ug
TP316541	Recombinant protein of human gamma-aminobutyric acid (GABA) A receptor, alpha 5 (GABRA5), 20 µg	20 ug