Gastric Inhibitory Polypeptide (GIP, Glucose-dependent Insulinotropic Polypeptide)
Référence MBS625731-5x0,05mL
Conditionnement : 5x0.05mL
Marque : MyBiosource
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Gastric Inhibitory Polypeptide (GIP) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS625731MBS625731 is an antibody targeting GIP. Also known as Gastric Inhibitory Polypeptide (GIP, Glucose-dependent Insulinotropic Polypeptide). Reactive in Porcine. Host: Rabbit. More details
Product Overview
Product Name
Gastric Inhibitory Polypeptide (GIP), Polyclonal Antibody
Full Product Name
Gastric Inhibitory Polypeptide (GIP, Glucose-dependent Insulinotropic Polypeptide)
Product Gene Name
anti-GIP antibody
Product Synonym Names
Anti -Gastric Inhibitory Polypeptide (GIP, Glucose-dependent Insulinotropic Polypeptide)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Porcine
Form/Format
Supplied as a lyophilized powder. Reconstitute with 50-100ul sterile ddH2O. Dilute further in 0.1M PBS, 1% BSA, 0.1% sodium azide.
Purity/Purification
Serum
Serum
Serum
Specificity
Recognizes porcine GIP.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
17,108 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (47035918..47045955, complement). Location: 17q21.3-q22
OMIM
137240
Immunogen
Pure porcine GIP
Product Categories/Family for anti-GIP antibody
Applications Tested/Suitable for anti-GIP antibody
Immunohistochemistry (IHC)
Application Notes for anti-GIP antibody
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Paraffin, frozen): 1:100-1:300 using FITC. Incubate overnight at 4ºC.
Dilution: Immunohistochemistry (Paraffin, frozen): 1:100-1:300 using FITC. Incubate overnight at 4ºC.
Other Notes
Small volumes of anti-GIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for GIP. It may not necessarily be applicable to this product.
NCBI Official Full Name
gastric inhibitory polypeptide
NCBI Official Synonym Full Names
gastric inhibitory polypeptide
NCBI Official Symbol
GIP
UniProt Protein Name
Gastric inhibitory polypeptide
UniProt Synonym Protein Names
Glucose-dependent insulinotropic polypeptide
Protein Family
Copia protein
UniProt Gene Name
GIP
UniProt Entry Name
GIP_HUMAN
NCBI Protein Information
gastric inhibitory polypeptide; OTTHUMP00000219839; glucose-dependent insulinotropic polypeptide
NCBI Summary for GIP
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq]
Show more UniProt Comments for GIP
GIP: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. Belongs to the glucagon family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q21.3-q22
Cellular Component: extracellular space; cell soma; endoplasmic reticulum lumen; extracellular region
Molecular Function: hormone activity
Biological Process: response to drug; response to peptide hormone stimulus; adult locomotory behavior; positive regulation of insulin secretion; female pregnancy; sensory perception of pain; response to amino acid stimulus; response to lipid; signal transduction; endocrine pancreas development; response to organic cyclic substance; memory; response to starvation; response to selenium ion; cellular protein metabolic process; response to glucose stimulus; response to axon injury; regulation of insulin secretion
Show more Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q21.3-q22
Cellular Component: extracellular space; cell soma; endoplasmic reticulum lumen; extracellular region
Molecular Function: hormone activity
Biological Process: response to drug; response to peptide hormone stimulus; adult locomotory behavior; positive regulation of insulin secretion; female pregnancy; sensory perception of pain; response to amino acid stimulus; response to lipid; signal transduction; endocrine pancreas development; response to organic cyclic substance; memory; response to starvation; response to selenium ion; cellular protein metabolic process; response to glucose stimulus; response to axon injury; regulation of insulin secretion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-GIP antibody
| Reference Product | PubMed Publications |
|---|---|
| GIPR antibody | >62 publications with GIP and GIPR |
Pathways associated with anti-GIP antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Class B/2 (Secretin Family Receptors) Pathway antibodies | Class B/2 (Secretin Family Receptors) Pathway Diagram |
| Diabetes Pathways antibodies | Diabetes Pathways Diagram |
| G Alpha (s) Signalling Events Pathway antibodies | G Alpha (s) Signalling Events Pathway Diagram |
| GPCR Downstream Signaling Pathway antibodies | GPCR Downstream Signaling Pathway Diagram |
| GPCR Ligand Binding Pathway antibodies | GPCR Ligand Binding Pathway Diagram |
| Glucagon-type Ligand Receptors Pathway antibodies | Glucagon-type Ligand Receptors Pathway Diagram |
| Incretin Synthesis, Secretion, And Inactivation Pathway antibodies | Incretin Synthesis, Secretion, And Inactivation Pathway Diagram |
| Integration Of Energy Metabolism Pathway antibodies | Integration Of Energy Metabolism Pathway Diagram |
| Regulation Of Insulin Secretion Pathway antibodies | Regulation Of Insulin Secretion Pathway Diagram |
| Signaling By GPCR Pathway antibodies | Signaling By GPCR Pathway Diagram |
Diseases associated with anti-GIP antibody
| Disease Name | Pubmed Publications |
|---|---|
| Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules Antibodies | >2426 publications with GIP and Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules |
| Diabetes Mellitus, Type 2 Antibodies | >311 publications with GIP and Diabetes Mellitus, Type 2 |
| Obesity Antibodies | >217 publications with GIP and Obesity |
| Insulin Resistance Antibodies | >153 publications with GIP and Insulin Resistance |
| Neoplasms Antibodies | >144 publications with GIP and Neoplasms |
| Mental Disorders Antibodies | >72 publications with GIP and Mental Disorders |
| Weight Loss Antibodies | >64 publications with GIP and Weight Loss |
| Adenoma Antibodies | >55 publications with GIP and Adenoma |
| Diabetes Complications Antibodies | >52 publications with GIP and Diabetes Complications |
| Neurologic Manifestations Antibodies | >40 publications with GIP and Neurologic Manifestations |
Organs/Tissues associated with anti-GIP antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Intestine Antibodies | >399 publications with GIP and Intestine |
| Stomach Antibodies | >146 publications with GIP and Stomach |