GFAP Antibody
Référence OAEE00400
Conditionnement : 0.1mg(C100)
Marque : Aviva Systems Biology
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for GFAP Antibody |
|---|
| Predicted Species Reactivity | Cat|Human|Porcine|Rat |
|---|---|
| Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | GF-01 |
| Isotype | IgG2b |
| Host | Mouse |
| Application | ICC|IHC-P|IP|WB |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Pellet of porcine brain cold-stable proteins after depolymerization of microtubules. |
| Purification | Purified |
| Concentration | 1 mg/ml |
| Specificity | The antibody GF-01 reacts with GFAP, the principal marker of astroglial cells in the central nervous system, which is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves. The GFAP protein runs on gels at ~55 kDa protein, usually associated with lower Mw bands which are thought to be proteolytic fragments and alternate transcripts from the single gene. |
| Formulation | Purified |
| Purity | > 95% (by SDS-PAGE) |
| Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Reference | Lukas Z, Draber P, Bucek J, Draberova E, Viklicky V, Staskova Z: Expression of vimentin and glial fibrillary acidic protein in human developing spinal cord. Histochem J. 1989 Dec;21(12):693-701. Bignami A, Eng LF, Dahl D, Uyeda CT: Localization of the glial fibrillary acidic protein in astrocytes byimmunofluorescence. Brain Res. 1972 Aug 25;43(2):429-35. Brenner M, Johnson AB, Boespflug-Tanguy O, Rodriguez D, Goldman JE, Messing A.: Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet. 2001 Jan;27(1):117-20. |
|---|---|
| Gene Symbol | GFAP |
| Gene Full Name | glial fibrillary acidic protein |
| Alias Symbols | ALXDRD, glial fibrillary acidic protein. |
| NCBI Gene Id | 2670 |
| Protein Name | Glial fibrillary acidic protein |
| Description of Target | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| Uniprot ID | P14136 |
| Protein Accession # | NP_001124491.1; NP_001229305.1; NP_002046.1 |
| Nucleotide Accession # | NM_001131019.2; NM_001242376.1; NM_002055.4 |
