Hispidin [555-55-5]
Référence T7792-1mg
Conditionnement : 1mg
Marque : TargetMol
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
Hispidin
Copy Product Info
Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties
Cas No. 555-55-5
For research use only—not for human use. No sales to individuals. Use as intended only.
Select Batch
Purity:98.27%
Appearance:Solid
Color:Yellow
COA LCMS HNMR
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties |
| In vitro | Hispidin from P. linteus exhibited quenching effects against DPPH radicals, superoxide radicals, and hydrogen peroxide in a dose-dependent manner. Intracellular reactive oxygen species scavenging activity of hispidin was approximately 55% at a concentration of 30 μM. In addition, hispidin was shown to inhibit hydrogen peroxide-induced apoptosis and increased insulin secretion in hydrogen peroxide-treated cells. These combined results indicate that hispidin may act as an antidiabetic and that this property occurs through preventing β-cells from the toxic action of reactive oxygen species in diabetes[1].Hispidin inhibits protein kinase C β (PKCβ ; IC50 = 2 μM) with no activity against alkaline phosphatase[2] |
| Molecular Weight | 246.22 |
| Formula | C13H10O5 |
| Cas No. | 555-55-5 |
| Smiles | Oc1cc(=O)cc(\C=C\c2ccc(O)c(O)c2)o1 |
| Relative Density. | 1.657 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (91.38 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (4.06 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||||||||||||||||||||||