HRP-Linked Polyclonal Antibody to Coilin (COIL)

Référence MBS2043192-0,5mL

Conditionnement : 0.5mL

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Coilin (COIL) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2043192
SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2043192 is an antibody targeting COIL. Also known as HRP-Linked Polyclonal Antibody to Coilin (COIL). Reactive in Human, Mouse. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Coilin (COIL), Polyclonal Antibody
Full Product Name
HRP-Linked Polyclonal Antibody to Coilin (COIL)
Product Gene Name
anti-COIL antibody
Product Synonym Names
CLN80; P80-Coilin
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: COIL (MBS2032220)
HRP Conjugated Antibody: COIL (MBS2043192)
Matching Pairs
HRP Conjugated Antibody: COIL (MBS2043192)
Immunogen: COIL (MBS2031767)
Molecular Weight
62,608 Da
OMIM
M58411 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
COIL (Ser319~Glu538)
Conjugation
HRP
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2032220
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-COIL antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-COIL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for COIL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
coilin
NCBI Official Synonym Full Names
coilin
NCBI Official Symbol
COIL
NCBI Official Synonym Symbols
CLN80; p80-coilin
UniProt Protein Name
Coilin
UniProt Synonym Protein Names
p80-coilin
Protein Family
Coilin
UniProt Gene Name
COIL
UniProt Synonym Gene Names
CLN80
NCBI Protein Information
coilin

NCBI Summary for COIL

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
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UniProt Comments for COIL

coilin: an ubiquitous protein found in nuclear coiled bodies (CBS), nuclear suborganelles involved in the post-transcriptional modification of snRNPs and small nucleolar RNAs. snRNPs undergo 2'-O-methylation and pseudouridylation in CBS. Differential methylation and phosphorylation of coilin likely influences localization among nuclear bodies and the composition and assembly of CBS. Located in the interchromatin space between the nucleolus and the nucleus.

Protein type: Oxidoreductase

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: Cajal body; membrane; nucleolus; nucleoplasm; nucleus

Molecular Function: identical protein binding; protein binding; protein C-terminus binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-COIL antibody

 Reference Product  PubMed Publications
 GCC1 antibody  >3 publications with COIL and GCC1
 POLI antibody  >2 publications with COIL and POLI
 SMN1 antibody  >2 publications with COIL and SMN1
 ATXN1 antibody  >1 publications with COIL and ATXN1

Diseases associated with anti-COIL antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3906 publications with COIL and Nervous System Diseases
 Hemorrhage Antibodies  >1549 publications with COIL and Hemorrhage
 Heart Defects, Congenital Antibodies  >612 publications with COIL and Heart Defects, Congenital
 Pain Antibodies  >591 publications with COIL and Pain
 Disease Models, Animal Antibodies  >458 publications with COIL and Disease Models, Animal
 Liver Diseases Antibodies  >357 publications with COIL and Liver Diseases
 Kidney Diseases Antibodies  >346 publications with COIL and Kidney Diseases
 Lung Diseases Antibodies  >303 publications with COIL and Lung Diseases
 Necrosis Antibodies  >287 publications with COIL and Necrosis
 Inflammation Antibodies  >285 publications with COIL and Inflammation

Organs/Tissues associated with anti-COIL antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3577 publications with COIL and Blood
 Brain Antibodies  >3392 publications with COIL and Brain
 Muscle Antibodies  >2288 publications with COIL and Muscle
 Heart Antibodies  >1739 publications with COIL and Heart
 Bone Antibodies  >1306 publications with COIL and Bone
 Eye Antibodies  >1022 publications with COIL and Eye
 Liver Antibodies  >774 publications with COIL and Liver
 Kidney Antibodies  >735 publications with COIL and Kidney
 Skin Antibodies  >623 publications with COIL and Skin
 Lung Antibodies  >599 publications with COIL and Lung