HRP-Linked Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 1 (PTGS1)

Référence MBS2046680-0,2mL

Conditionnement : 0.2mL

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Prostaglandin Endoperoxide Synthase 1 (PTGS1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2046680
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MBS2046680 is an antibody targeting PTGS1. Also known as HRP-Linked Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 1 (PTGS1). Reactive in Human, Rat. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Prostaglandin Endoperoxide Synthase 1 (PTGS1), Polyclonal Antibody
Full Product Name
HRP-Linked Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 1 (PTGS1)
Product Gene Name
anti-PTGS1 antibody
Product Synonym Names
COX1; COX3; PCOX1; PGG/HS; PGHS1; PHS1; PTGHS; Cyclooxygenase 1; Prostaglandin H2 Synthase 1; Prostaglandin G/H Synthase And Cyclooxygenase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: PTGS1 (MBS2007299)
HRP Conjugated Antibody: PTGS1 (MBS2046680)
Matching Pairs
HRP Conjugated Antibody: PTGS1 (MBS2046680)
Immunogen: PTGS1 (MBS2029439)
Molecular Weight
72,010 Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
PTGS1 (Gly367~Leu599)
Conjugation
HRP
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2007299
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PTGS1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-PTGS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTGS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
prostaglandin-endoperoxide synthase 1
NCBI Official Synonym Full Names
prostaglandin-endoperoxide synthase 1
NCBI Official Symbol
PTGS1
NCBI Official Synonym Symbols
COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1
UniProt Protein Name
Prostaglandin G/H synthase 1
UniProt Synonym Protein Names
Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
Protein Family
Prostaglandin G/H synthase
UniProt Gene Name
PTGS1
UniProt Synonym Gene Names
COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1
NCBI Protein Information
prostaglandin G/H synthase 1

NCBI Summary for PTGS1

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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UniProt Comments for PTGS1

COX-1: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Homodimer. Belongs to the prostaglandin G/H synthase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.99.1; Lipid Metabolism - arachidonic acid; Oxidoreductase

Chromosomal Location of Human Ortholog: 9q33.2

Cellular Component: cytoplasm; endoplasmic reticulum membrane; Golgi apparatus; intracellular membrane-bound organelle; nucleus

Molecular Function: peroxidase activity; prostaglandin-endoperoxide synthase activity

Biological Process: cyclooxygenase pathway; prostaglandin biosynthetic process; regulation of blood pressure; xenobiotic metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PTGS1 antibody

 Reference Product  PubMed Publications
 ALOX5 antibody  >103 publications with PTGS1 and ALOX5
 PLA2G4A antibody  >85 publications with PTGS1 and PLA2G4A
 PTGES antibody  >12 publications with PTGS1 and PTGES
 PTGIS antibody  >6 publications with PTGS1 and PTGIS
 ALOX12 antibody  >5 publications with PTGS1 and ALOX12
 PTGES2 antibody  >4 publications with PTGS1 and PTGES2
 PTGES3 antibody  >3 publications with PTGS1 and PTGES3
 TBXAS1 antibody  >3 publications with PTGS1 and TBXAS1
 PTGDS antibody  >2 publications with PTGS1 and PTGDS

Pathways associated with anti-PTGS1 antibody

 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 COX Reactions Pathway antibodies  COX Reactions Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Phase 1 - Functionalization Of Compounds Pathway antibodies  Phase 1 - Functionalization Of Compounds Pathway Diagram

Diseases associated with anti-PTGS1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >911 publications with PTGS1 and Inflammation
 Neoplasms Antibodies  >649 publications with PTGS1 and Neoplasms
 Gastrointestinal Diseases Antibodies  >580 publications with PTGS1 and Gastrointestinal Diseases
 Cardiovascular Diseases Antibodies  >434 publications with PTGS1 and Cardiovascular Diseases
 Drug Toxicity Antibodies  >330 publications with PTGS1 and Drug Toxicity
 Pain Antibodies  >323 publications with PTGS1 and Pain
 Carcinoma Antibodies  >268 publications with PTGS1 and Carcinoma
 Necrosis Antibodies  >256 publications with PTGS1 and Necrosis
 Edema Antibodies  >213 publications with PTGS1 and Edema
 Heart Diseases Antibodies  >141 publications with PTGS1 and Heart Diseases

Organs/Tissues associated with anti-PTGS1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1170 publications with PTGS1 and Blood
 Vascular Antibodies  >647 publications with PTGS1 and Vascular
 Brain Antibodies  >351 publications with PTGS1 and Brain
 Stomach Antibodies  >347 publications with PTGS1 and Stomach
 Muscle Antibodies  >326 publications with PTGS1 and Muscle
 Kidney Antibodies  >285 publications with PTGS1 and Kidney
 Heart Antibodies  >227 publications with PTGS1 and Heart
 Intestine Antibodies  >212 publications with PTGS1 and Intestine
 Lung Antibodies  >201 publications with PTGS1 and Lung
 Liver Antibodies  >185 publications with PTGS1 and Liver