Human CREB1 Antibody : APC (Phospho-Ser133)
Référence OAAQ00094-10tests
Conditionnement : 10Tests
Marque : Aviva Systems Biology
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Human CREB1 Antibody : APC (Phospho-Ser133)
Human CREB1 Antibody : APC (Phospho-Ser133) (OAAQ00094)
| Datasheets/Manuals | Printable datasheet for OAAQ00094 |
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| Tested Species Reactivity | Human, Mouse |
|---|---|
| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
| Clonality | Monoclonal |
| Clone | CREBS133-4D11 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | APC: Allophycocyanin |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser133 of human phospho CREB |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Ser133 |
| Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Reference | 1. Mayr B, et al. (2001). Nat. Rev. Mol. Cell Biol. 2: 599-609. 2.Sandoval S, et al. (2009) Adv. Hematol. 2009:634292. 3. Lonze BE, et. al. (2002) Neuron 34: 371-85. 4. Chrivia JC, et al. (1993) Nature 365: 855-9. 5. Kundu TK, et al. (2000) Mol. Cell 6: 551-61. 6. Shaywitz AJ, et al. (1999) Annu. Rev. Biochem. 68: 821-61. 7. Conkright MD, et al. (2003) Mol. Cell 12: 413-23. 8. Bohm M, et al. (1995) Cell Growth Differ. 6: 291-302. 9. Xing J, et al. (1996) Science 273: 959-63. 10. Kwon EM, et al. (2000) 95: 2552-8. |
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| Gene Symbol | CREB1 |
| Gene Full Name | cAMP responsive element binding protein 1 |
| Alias Symbols | CREB, CREB-1 |
| NCBI Gene Id | 1385 |
| Protein Name | cyclic AMP-responsive element-binding protein 1 |
| Description of Target | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. |
| Uniprot ID | P16220 |
| Protein Accession # | NP_004370.1 |
| Nucleotide Accession # | NM_004379.4 |
