600336 | Human GH Biovalley

Recombinant Active Protein

Cat. No.

600336

Unit

0.5 mg

Description

Growth Hormone (GH) is an important growth factor made in and secreted throughout the body by the anterior pituitary gland. It stimulates growth and cell reproduction and regeneration in humans and other animals. The inability to appropriately produce or respond to GH results in diseases of decreased stature in children and adults. Although GH is used to treat several growth disorders, it is thought to be a very complex hormone with many of its functions yet to be uncovered. Human GH is produced in E.coli. Recombinant human GH is non-glycosylated protein, containing 192 amino acids, with a molecular weight of 22.2 kDa.

Spec Container

Datasheet

Format

Each vial contains 0.5 mg of lyophilized protein. Reconstitute with 0.5 ml sterile deionized water for a final concentration of 1 mg/ml.

Alternate Names

Growth hormone; Somatotropin; GH; GH-N; Pituitary growth hormone; Growth hormone 1; GH1

Accession No.

P01241

22200 Da

Sequence

MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFEEAYIPKE QKYSFLQNPQ TSLCFSESIP TPSNREETQQ KSNLELLRIS LLLIQSWLEP VQFLRSVFAN SLVYGASDSN VYDLLKDLEE GIQTLMGRLE DGSPRTGQIF KQTYSKFDTN SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC GF

Source

E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Purity

Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Application Notes

The activity is determined by the ability to induce proliferation of PDF 9D11 cells for this effect and is typically 0.5-0.8 ng/mL. Specific activity: 2 x 10e6 units/mg

Storage

Store at -20C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.

Images

For research use only, not for diagnostic or therapeutic procedures.

Human GH

Référence 600336

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Marque : Abbiotec

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Spec Container