OPMA04367 | Human HDL 2 Subfraction Protein Biovalley

Datasheets/Manuals	Printable datasheet for OPMA04367

Product Info
Predicted Species Reactivity	Human
Product Format	Liquid Standard buffer, 100mM Sodium Chloride, 10mM Tris, 1mM EDTA (pH 7.4) with 1mM Sodium Azide
Application	Specific methodologies have not been tested using this product.
Additional Information	Inactivation: Not Applicable
Reconstitution and Storage	Store at 2-8°C. Do not freeze.
Purification	Purified
Concentration	1.0 mg/ml (BioRad DC)
Purity	Sequential Density Ultracentrifugation at d 1.063-1.125 Devoid of VLDL, IDL, LDL, and HDL₃
Specificity	Lipoprotein, High Density (HDL) 2 Subfraction
Source	Human Normolipidemic Plasma
Warning	This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of distilled water.

Protein interactions

Biological pathways

Name	# of Products
Cholesterol efflux	92
Cholesterol homeostasis	162
Diacylglycerol catabolic process	9
High-density lipoprotein particle assembly	58
High-density lipoprotein particle clearance	64
High-density lipoprotein particle remodeling	84
Interspecies interaction between organisms	817
Lipoprotein metabolic process	108
Low-density lipoprotein particle remodeling	69
Negative regulation of cholesterol import	16
Negative regulation of cholesterol transporter activity	9
Negative regulation of cytokine secretion involved in immune response	90
Negative regulation of lipase activity	10
Negative regulation of lipid catabolic process	87
Negative regulation of very-low-density lipoprotein particle remodeling	45
Phosphatidylcholine biosynthetic process	45
Phospholipid catabolic process	33
Phospholipid efflux	83
Positive regulation of cholesterol esterification	75
Positive regulation of interleukin-8 biosynthetic process	38
Positive regulation of lipid catabolic process	29
Protein folding	257
Regulation of protein stability	34
Response to glucose stimulus	59
Reverse cholesterol transport	103
Triglyceride metabolic process	52
Triglyceride-rich lipoprotein particle remodeling	9

Biological process

Name	# of Products
Acute inflammatory response	17
Cellular lipid metabolic process	114
Cholesterol efflux	28
Cholesterol homeostasis	56
Cholesterol metabolic process	72
Diacylglycerol catabolic process	2
High-density lipoprotein particle assembly	8
High-density lipoprotein particle clearance	8
High-density lipoprotein particle remodeling	17
Interspecies interaction between organisms	281
Lipid metabolic process	172
Lipoprotein metabolic process	40
Low-density lipoprotein particle remodeling	11
Negative regulation of cholesterol import	2
Negative regulation of cholesterol transport	4
Negative regulation of cholesterol transporter activity	1
Negative regulation of cytokine secretion involved in immune response	13
Negative regulation of lipase activity	3
Negative regulation of lipid catabolic process	21
Negative regulation of very-low-density lipoprotein particle remodeling	5
Organ regeneration	59
Phosphatidylcholine biosynthetic process	13
Phospholipid catabolic process	10
Phospholipid efflux	14
Positive regulation of cholesterol esterification	9
Positive regulation of interleukin-8 biosynthetic process	11
Positive regulation of lipid catabolic process	9
Protein folding	164
Regulation of intestinal cholesterol absorption	9
Regulation of protein stability	19
Response to drug	323
Response to estrogen stimulus	71
Response to glucocorticoid stimulus	109
Response to glucose stimulus	72
Reverse cholesterol transport	22
Small molecule metabolic process	825
Transport	555
Triglyceride metabolic process	32
Triglyceride-rich lipoprotein particle remodeling	3

Cellular components

Name	# of Products
Chylomicron	13
Endoplasmic reticulum lumen	87
Extracellular region	1573
Extracellular space	884
High-density lipoprotein particle	22
Spherical high-density lipoprotein particle	9
Very-low-density lipoprotein particle	15

Protein function

Name	# of Products
Apolipoprotein receptor binding	46
Cholesterol binding	131
Cholesterol transporter activity	83
High-density lipoprotein particle binding	58
High-density lipoprotein particle receptor binding	46
Lipase inhibitor activity	24
Lipid binding	364
Lipid transporter activity	92
Phosphatidylcholine binding	23
Phosphatidylcholine-sterol O-acyltransferase activator activity	61
Phospholipid binding	197
Protein binding	12191
Protein heterodimerization activity	1132
Protein homodimerization activity	1852

Human HDL 2 Subfraction Protein