Human IgG Rabbit pAb
Référence MBS8543349-0,1mL-Biotin
Conditionnement : 0.1mL(Biotin)
Marque : MyBiosource
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Human IgG Rabbit pAb
IgG Secondary Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8543349IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids,… More details
Product Overview
Online Datasheet in PDFProduct Name
IgG, Secondary Antibody
Full Product Name
Human IgG Rabbit pAb
Product Gene Name
IgG secondary antibody
Product Synonym Names
G1m marker; G2m marker; G3m marker; G4m marker; HDC; Heavy chain disease protein; Human immunglobulin G; Ig gamma 1 chain C region; Ig gamma 2 chain C region; Ig gamma 3 chain C region; Ig gamma 4 chain C region; IgG heavy chain locus; IGHG1; IGHG2; IGHG3; IGHG4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Purity/Purification
Affinity Chromatography
Preparation and Storage
Store at 4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.
Applications Tested/Suitable for IgG secondary antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for IgG secondary antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IHC: 1:50-1:200
Other Notes
Small volumes of IgG secondary antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for IgG purchase
MBS8543349 is a secondary antibody targeting IgG. Also known as Human IgG Rabbit pAb. Reactive in Human. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for IgG. It may not necessarily be applicable to this product.
NCBI Official Full Name
Immunoglobulin heavy constant gamma 1
NCBI Official Synonym Full Names
immunoglobulin heavy constant gamma 1 (G1m marker)
NCBI Official Symbol
IGHG1
UniProt Protein Name
Ig gamma-1 chain C region
Protein Family
IgG receptor
UniProt Gene Name
IGHG1
UniProt Entry Name
IGHG1_HUMAN
UniProt Comments for IgG
IGHG1: Defects in IGHG1 are a cause of multiple myeloma (MM). MM is a malignant tumor of plasma cells usually arising in the bone marrow and characterized by diffuse involvement of the skeletal system, hyperglobulinemia, Bence-Jones proteinuria and anemia. Complications of multiple myeloma are bone pain, hypercalcemia, renal failure and spinal cord compression. The aberrant antibodies that are produced lead to impaired humoral immunity and patients have a high prevalence of infection. Amyloidosis may develop in some patients. Multiple myeloma is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance (MGUS) to plasma cell leukemia. A chromosomal aberration involving IGHG1 is found in multiple myeloma. Translocation t(11;14)(q13;q32) with the IgH locus. Translocation t(11;14)(q13;q32) with CCND1; translocation t(4;14)(p16.3;q32.3) with FGFR3; translocation t(6;14)(p25;q32) with IRF4.
Protein type: Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: extracellular space; extracellular region
Molecular Function: protein binding; antigen binding
Biological Process: innate immune response; complement activation, classical pathway; complement activation
Disease: Myeloma, Multiple
Show more Protein type: Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: extracellular space; extracellular region
Molecular Function: protein binding; antigen binding
Biological Process: innate immune response; complement activation, classical pathway; complement activation
Disease: Myeloma, Multiple
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with IgG secondary antibody
| Reference Product | PubMed Publications |
|---|---|
| IGKC secondary antibody | >1 publications with IgG and IGKC |
Pathways associated with IgG secondary antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Classical Antibody-mediated Complement Activation Pathway antibodies | Classical Antibody-mediated Complement Activation Pathway Diagram |
| Complement Cascade Pathway antibodies | Complement Cascade Pathway Diagram |
| Creation Of C4 And C2 Activators Pathway antibodies | Creation Of C4 And C2 Activators Pathway Diagram |
| FCGR Activation Pathway antibodies | FCGR Activation Pathway Diagram |
| Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies | Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram |
| IL4-mediated Signaling Events Pathway antibodies | IL4-mediated Signaling Events Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Initial Triggering Of Complement Pathway antibodies | Initial Triggering Of Complement Pathway Diagram |
| Innate Immune System Pathway antibodies | Innate Immune System Pathway Diagram |
| Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies | Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram |
Organs/Tissues associated with IgG secondary antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >11 publications with IgG and Blood |
| Lymph Antibodies | >2 publications with IgG and Lymph |
| Lymph Node Antibodies | >2 publications with IgG and Lymph Node |
| Intestine Antibodies | >2 publications with IgG and Intestine |
| Skin Antibodies | >2 publications with IgG and Skin |
| Bone Antibodies | >1 publications with IgG and Bone |
| Bone Marrow Antibodies | >1 publications with IgG and Bone Marrow |
| Thyroid Antibodies | >1 publications with IgG and Thyroid |
| Pancreas Antibodies | >1 publications with IgG and Pancreas |
| Uterus Antibodies | >1 publications with IgG and Uterus |