IgG4 (Biotin)
Référence MBS6249042-5x0,1mL
Conditionnement : 5x0.1mL
Marque : MyBiosource
IgG4 Secondary Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6249042MBS6249042 is a secondary antibody targeting IgG4. Also known as IgG4 (Biotin). Reactive in Human. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
IgG4, Secondary Antibody
Full Product Name
IgG4 (Biotin)
Product Gene Name
IgG4 secondary antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H2426
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes the heavy chain of human IgG4 at an epitope in the Fc region. Does not crossreact with IgG1, IgG2, IgG3, IgM or IgA. Species Crossreactivity: chimpanzee
Preparation and Storage
Store at -20 degree C.
Applications Tested/Suitable for IgG4 secondary antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Product References and Citations for IgG4 secondary antibody
1. Jefferis, R. et al. (1985). Immunology Letters. 10:223-252. 2. Agaimy, A. et al. (2010) Am J Surg Pathol. 34:271-8. 3. Strehl, J.D. et al. (2011) Numerous IgG4-positive plasma cells are ubiquitous in diverse localised non-specific chronic inflammatory conditions and need to be distinguished from IgG4-related systemic disorders. J Clin Pathol. Jan 12. 4. Black, C.M. et al. (1991) Immunology. 72:94-8. 5. Fernandez-Becerra, C. (2010) Malar J. 9:29. 6. Lee, H.W. et al. (2008) Korean J Parasitol. 46:195-8.
Other Notes
Small volumes of IgG4 secondary antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for IgG4. It may not necessarily be applicable to this product.
NCBI Official Full Name
Ig gamma-4 chain C region
NCBI Official Synonym Full Names
immunoglobulin heavy constant gamma 4 (G4m marker)
NCBI Official Symbol
IGHG4
UniProt Protein Name
Ig gamma-4 chain C region
UniProt Gene Name
IGHG4
UniProt Entry Name
IGHG4_HUMAN
UniProt Comments for IgG4
IGHG4:
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: extracellular space; extracellular region
Molecular Function: antigen binding
Biological Process: innate immune response; complement activation, classical pathway; complement activation
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: extracellular space; extracellular region
Molecular Function: antigen binding
Biological Process: innate immune response; complement activation, classical pathway; complement activation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with IgG4 secondary antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Classical Antibody-mediated Complement Activation Pathway antibodies | Classical Antibody-mediated Complement Activation Pathway Diagram |
| Complement Cascade Pathway antibodies | Complement Cascade Pathway Diagram |
| Creation Of C4 And C2 Activators Pathway antibodies | Creation Of C4 And C2 Activators Pathway Diagram |
| FCGR Activation Pathway antibodies | FCGR Activation Pathway Diagram |
| Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies | Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Initial Triggering Of Complement Pathway antibodies | Initial Triggering Of Complement Pathway Diagram |
| Innate Immune System Pathway antibodies | Innate Immune System Pathway Diagram |
| Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies | Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram |
| Role Of Phospholipids In Phagocytosis Pathway antibodies | Role Of Phospholipids In Phagocytosis Pathway Diagram |
Organs/Tissues associated with IgG4 secondary antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >3 publications with IgG4 and Blood |


