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> KLF2 (Kruppel-like Factor 2, Lung Kruppel-like Factor, LKLF, Lung Kruppel-like Zinc Finger Transcription Factor, Kruppel-like Factor LKLF)

KLF2 (Kruppel-like Factor 2, Lung Kruppel-like Factor, LKLF, Lung Kruppel-like Zinc Finger Transcription Factor, Kruppel-like Factor LKLF)

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Référence K1891-37C-100ug

Conditionnement : 100ug

Marque : US Biological

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K1891-37CKLF2 (Kruppel-like Factor 2, Lung Kruppel-like Factor, LKLF, Lung Kruppel-like Zinc Finger Transcription Factor, Kruppel-like Factor LKLF)

Specifications
Clone TypeMonoclonal
Hostmouse
Sourcehuman
Swiss ProtQ9Y5W3
IsotypeIgG2b
GradeAffinity Purified
ApplicationsIC
CrossreactivityHu
Shipping TempBlue Ice
Storage Temp-20°C

KLF2 (Kruppel-like factor 2; endothelium, monocytes, Taa in length. It contains an activation domain aa1-110, an inhibitory domain aa111-267, and three C2H2-type zinc-finger regions aa272-354. There is one potential splice form that shows a premature truncation after Asp224. Over aa71-168, human KLF2 is 82aa identical to mouse KLF2. also LKLF) is a lung-associated, 37kD member of the Kruppel C2H2-type zinc-finger protein family. KLF2 is found in airway epithelium, and B cells. It is a transcription factor that regulates multiple genes, many of which are involved in cell migration.

Applications:
Suitable for use in Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Immunocytochemistry: 8-25ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Applications
Product Type: Mab|Isotype: IgG2b|Clone No: 11n121|Host: mouse|Source: human|Concentration: ~0.5mg/ml (after reconstitution) |Form: Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.|Purity: Purified by Protein A affinity chromatography.|Immunogen: Recombinant corresponding to Pro71-Pro168 (predicted) from human KLF2 (predicted) expressed in E. coli.|Specificity: Recognizes human KLF2. Species sequence homology: Recombinant human KLF17. No cross-reactivity with KLF1, 4, 5, 6, 10, 12, 17, recombinant mouse KLF4 or 15 (10%).||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Recombinant corresponding to Pro71-Pro168 (predicted) from human KLF2 (predicted) expressed in E. coli.
Form
Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human KLF2. Species sequence homology: Recombinant human KLF17. No cross-reactivity with KLF1, 4, 5, 6, 10, 12, 17, recombinant mouse KLF4 or 15 (10%).