Limonene [138-86-3]

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Référence T75431-5mL

Conditionnement : 5mL

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Limonene

(Synonyms: Dipentene, (±)-α-Limonene, (±)-Limonene) Copy Product Info
Limonene (Dipentene) is a monoterpene found in citrus plants such as lemon, orange, and grape, widely used in cosmetics and household products as a fragrance, with antimicrobial, antiproliferative, antioxidant, and anti-inflammatory properties.
Limonene
Cas No. 138-86-3
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent

Product Information

Bioactivity
Description
Limonene (Dipentene) is a monoterpene found in citrus plants such as lemon, orange, and grape, widely used in cosmetics and household products as a fragrance, with antimicrobial, antiproliferative, antioxidant, and anti-inflammatory properties.
In vitro
Limonene exerts anti-inflammatory effects by reducing pro-inflammatory cytokines (TNF-α, IL-1β, COX-2), inhibiting TLR4/NF-κB/AP-1 but not the IRF3 signaling pathway, and regulating oxidative stress through Nrf2 activation. [1]
Limonene treatment inhibits UVB-induced α-MSH secretion and then suppresses melanocortin (POMC) by inhibiting p53 transcriptional activation. [2]
In vivo
Limonene (100 and 200 mg/kg, orally administered) in LPS mouse models mitigated the decline in renal function due to LPS induction, resulting in reduced serum urea and creatinine levels in mice. [1]
Limonene (20 mg/kg, intrabitoneally administered) reduced serum and brain nitrite levels and decreased the expression of IL-1β and TNF-α in the hippocampus of MS-stressed mice. [3]
SynonymsDipentene, (±)-α-Limonene, (±)-Limonene
Chemical Properties
Molecular Weight136.23
FormulaC10H16
Cas No.138-86-3
SmilesC=C(C)C1CC=C(C)CC1
Relative Density.0.86 g/mL at 20 °C (lit.)
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 80 mg/mL (587.24 mM), Sonication is recommended.
Solution Preparation Table
Ethanol
1mg5mg10mg50mg
1 mM7.3405 mL36.7026 mL73.4053 mL367.0264 mL
5 mM1.4681 mL7.3405 mL14.6811 mL73.4053 mL
10 mM0.7341 mL3.6703 mL7.3405 mL36.7026 mL
20 mM0.3670 mL1.8351 mL3.6703 mL18.3513 mL
50 mM0.1468 mL0.7341 mL1.4681 mL7.3405 mL
100 mM0.0734 mL0.3670 mL0.7341 mL3.6703 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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Related Tags: Limonene chemical structure | Limonene in vivo | Limonene in vitro | Limonene formula | Limonene molecular weight