LSN3106729 hydrochloride [2704316-82-3]

Référence T36967-5mg

Conditionnement : 5mg

Marque : TargetMol

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LSN3106729 hydrochloride

Copy Product Info
LSN3106729 hydrochloride, the metabolite of Abemaciclib , is a CDK inhibitor with antitumor activity. LSN3106729 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].
LSN3106729 hydrochloride
Cas No. 2704316-82-3
Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Description
LSN3106729 hydrochloride, the metabolite of Abemaciclib , is a CDK inhibitor with antitumor activity. LSN3106729 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].
Chemical Properties
Molecular Weight531.00
FormulaC25H29ClF2N8O
Cas No.2704316-82-3
SmilesCl.FC=1C=NC(=NC1C=2C=C(F)C=3N=C(N(C3C2)C(C)C)CO)NC4=NC=C(C=C4)CN5CCNCC5
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 125 mg/mL (235.4 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8832 mL9.4162 mL18.8324 mL94.1620 mL
5 mM0.3766 mL1.8832 mL3.7665 mL18.8324 mL
10 mM0.1883 mL0.9416 mL1.8832 mL9.4162 mL
20 mM0.0942 mL0.4708 mL0.9416 mL4.7081 mL
50 mM0.0377 mL0.1883 mL0.3766 mL1.8832 mL
100 mM0.0188 mL0.0942 mL0.1883 mL0.9416 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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