MGP Polyclonal Antibody
Référence MBS448121-0,8mg
Conditionnement : 0.8mg
Marque : MyBiosource
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MGP Antibody – Goat Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS448121SPECIAL PROMOTIONAL PRICING for a limited time
Goat polyclonal antibody to MGP. This protein is secreted and likely to act as an inhibitor of bone formation. It is found in the organic matrix of bone and cartilage and defects in the gene are a cause of Keutel syndrome. More details
Product Overview
Online Datasheet in PDFProduct Name
MGP, Polyclonal Antibody
Full Product Name
MGP Polyclonal Antibody
Product Gene Name
anti-MGP antibody
Product Synonym Names
Anti-MGP; GIG36; matrix Gla protein; MGLAP; NTI antibody
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Zebrafish
Form/Format
Polyclonal antibody supplied as a 200 ul (4 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Concentration
4 mg/ml (lot specific)
Specificity
Detects endogenous levels of MGP protein using 5 days zebrafish embryos lysates.
Preparation and Storage
Store at -20°C for long term storage.
Store at 2-8°C for up to one month.
Store at 2-8°C for up to one month.
Applications Tested/Suitable for anti-MGP antibody
Western Blot (WB)
Application Notes for anti-MGP antibody
WB: 1:250 - 1:2,000
Other Notes
Small volumes of anti-MGP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MGP purchase
MBS448121 is an antibody targeting MGP. Also known as MGP Polyclonal Antibody. Reactive in Zebrafish. Host: Goat.
Additional Details
NCBI/Uniprot data below describe general gene information for MGP. It may not necessarily be applicable to this product.
NCBI Official Full Name
MGP, partial
NCBI Official Synonym Full Names
matrix Gla protein
NCBI Official Symbol
MGP
NCBI Official Synonym Symbols
NTI; GIG36; MGLAP
UniProt Protein Name
Matrix Gla protein
UniProt Synonym Protein Names
Cell growth-inhibiting gene 36 protein
Protein Family
Matrix Gla protein
UniProt Gene Name
MGP
UniProt Synonym Gene Names
MGLAP; MGP
UniProt Entry Name
MGP_HUMAN
NCBI Protein Information
matrix Gla protein
UniProt Comments for MGP
MGP: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. Defects in MGP are the cause of Keutel syndrome (KS). KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia. Belongs to the osteocalcin/matrix Gla protein family.
Protein type: Extracellular matrix; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: extracellular matrix; proteinaceous extracellular matrix
Molecular Function: extracellular matrix structural constituent; protein binding; structural constituent of bone
Biological Process: cartilage condensation
Disease: Keutel Syndrome
Show more Protein type: Extracellular matrix; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: extracellular matrix; proteinaceous extracellular matrix
Molecular Function: extracellular matrix structural constituent; protein binding; structural constituent of bone
Biological Process: cartilage condensation
Disease: Keutel Syndrome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-MGP antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Endochondral Ossification Pathway antibodies | Endochondral Ossification Pathway Diagram |
| Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway antibodies | Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway Diagram |
Diseases associated with anti-MGP antibody
| Disease Name | Pubmed Publications |
|---|---|
| Vascular Calcification Antibodies | >208 publications with MGP and Vascular Calcification |
| Cardiovascular Diseases Antibodies | >180 publications with MGP and Cardiovascular Diseases |
| Heart Diseases Antibodies | >81 publications with MGP and Heart Diseases |
| Kidney Diseases Antibodies | >81 publications with MGP and Kidney Diseases |
| Disease Models, Animal Antibodies | >42 publications with MGP and Disease Models, Animal |
| Inflammation Antibodies | >34 publications with MGP and Inflammation |
| Hypertension Antibodies | >27 publications with MGP and Hypertension |
| Carcinoma Antibodies | >22 publications with MGP and Carcinoma |
| Necrosis Antibodies | >20 publications with MGP and Necrosis |
| Hypertrophy Antibodies | >13 publications with MGP and Hypertrophy |
Organs/Tissues associated with anti-MGP antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Bone Antibodies | >277 publications with MGP and Bone |
| Vascular Antibodies | >272 publications with MGP and Vascular |
| Blood Antibodies | >214 publications with MGP and Blood |
| Muscle Antibodies | >131 publications with MGP and Muscle |
| Kidney Antibodies | >125 publications with MGP and Kidney |
| Connective Tissue Antibodies | >93 publications with MGP and Connective Tissue |
| Heart Antibodies | >82 publications with MGP and Heart |
| Brain Antibodies | >52 publications with MGP and Brain |
| Lung Antibodies | >45 publications with MGP and Lung |
| Liver Antibodies | >43 publications with MGP and Liver |