Mirvetuximab [1453084-36-0]
Référence T76766-1mg
Conditionnement : 1mg
Marque : TargetMol
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Mirvetuximab
(Synonyms: M9346A) Copy Product Info
Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form antibody-drug conjugates for the treatment of ovarian cancer and other FRα-positive cancers.
Cas No. 1453084-36-0
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
COA SDS-PAGE SEC-HPLC Instruction Manual of Inhibitory Antibody
Product Information
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form antibody-drug conjugates for the treatment of ovarian cancer and other FRα-positive cancers. |
| Endotoxin | <1.0 EU/mg |
| Synonyms | M9346A |
| Reactivity | Human |
| Verified Activity | Immobilized Human FRa Protein （ECD, His) at 2 μg/mL (30 μL/well) can bind Mirvetuximab. The EC50 is 9.298 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | 2348 |
| Uniprot ID | P15328 |
| Target | FOLR1/FRA |
| Molecular Weight | 145.96 kDa |
| Cas No. | 1453084-36-0 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control | Human IgG1 kappa, Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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