Conditionnement : 1kit
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Adam17 |
| Locus ID | 11491 |
| Components | GA200063G1, Adam17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200063G2, Adam17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200063G3, Adam17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001277266, NM_001291871, NM_009615, NR_102380, NR_120376 |
| UniProt ID | Q9Z0F8 |
| Synonyms | CD156b; Tace |
| Summary | This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that is involved in the proteolytic release of membrane-bound proteins in a process called ectodomain shedding. Mice lacking the encoded protein die in utero or fail to survive beyond one week of age. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. provided by RefSeq, May 2016 |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN500818 | Adam17 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |