NFE2L2 Antibody - middle region
Référence OAGA02126
Conditionnement : 100ul
Marque : Aviva Systems Biology
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NFE2L2 Antibody - middle region (OAGA02126)
| Datasheets/Manuals | Printable datasheet for NFE2L2 Antibody - middle region (OAGA02126) |
|---|
| Predicted Species Reactivity | Alligator|Avian|Human|Mouse|Plant|Rat|Zebrafish |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | CHIP|FACS|ICC|IF|IHC-P|IP|WB |
| Additional Information | Positive Controls: C8D30 , 3xFlag-human NFE2L2-transfected 293T , MDA-MB-231 nuclear extract , MDA-MB-231 nuclear extract (30uM tBHQ, 4hr) , HepG2 (10 uM MG132 treatment for 15 hr) Cellular Localization: Cytoplasm , cytosol , Nucleus |
| Reconstitution and Storage | -20°C or -80°C|2°C to 8°C |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human NRF2. The exact sequence is proprietary. |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Rhesus Monkey (99%), Bovine (84%) |
| Concentration | 0.31 mg/ml |
| Application Info | ICC/IF: 1:100-1:1000 IHC-P 1:100-1:1000 IP 1:100-1:500 WB 1:500-1:3000 CHIP: Assay-dependent dilution IHC: Assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. |
| Gene Symbol | NFE2L2 |
|---|---|
| Gene Full Name | nuclear factor, erythroid 2-like 2 |
| Alias Symbols | HEBP1, IMDDHH, Nrf-2, NRF2, nuclear factor erythroid 2-related factor 2, nuclear factor erythroid-derived 2-like 2, Nuclear factor, erythroid derived 2, like 2. |
| NCBI Gene Id | 4780 |
| Protein Name | Nuclear factor erythroid 2-related factor 2 |
| Description of Target | Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region. |
| Uniprot ID | Q16236 |
| Molecular Weight | 68 kDa |
