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> p53 (TP53) Mouse Monoclonal Antibody [Clone ID: OTI5E2]

p53 (TP53) Mouse Monoclonal Antibody [Clone ID: OTI5E2]

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Référence TA502870

Conditionnement : 100ul

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p53 (TP53) Mouse Monoclonal Antibody [Clone ID: OTI5E2]

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SKU
TA502870
TP53 mouse monoclonal antibody, clone OTI5E2 (formerly 5E2)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
 

View other "p53 or NM_000546" antibodies

Specifications
Product Data
Clone Name OTI5E2
Application FC, IF, IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human, Monkey, Mouse
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TP53 (NP_000537) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 43.5 kDa
Gene Name tumor protein p53
Database Link
Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. provided by RefSeq
Synonyms BCC7; LFS1; P53; TRP53
Reference Data
Protein Categories ADC Targets, Cancer: Bladder, Cancer: Brain and CNS, Cancer: Endocrine, Cancer: Gastrointestinal, Cancer: Gynecologic, Cancer: Haematopoietic and Lymphoid, Cancer: Head and Neck, Cancer: Lung, Cancer: Sarcoma, Cancer: Skin, Cardiovascular diseases, Growth Factors, Intracellular Proteins, Nervous system Diseases, Transciption Factors
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Protein Pathways Amyotrophic lateral sclerosis (ALS), Apoptosis, Basal cell carcinoma, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, Glioma, Huntington's disease, MAPK signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer, Thyroid cancer, Wnt signaling pathway
Product Manuals
FAQs
  • Antibody and Western Standard
SDS
SKU Description Size
CF502870 Carrier-free (BSA/glycerol-free) TP53 mouse monoclonal antibody, clone OTI5E2 (formerly 5E2) 100 ug
TA502870AM TP53 mouse monoclonal antibody, clone OTI5E2 (formerly 5E2), Biotinylated 100 ul
TA502870BM TP53 mouse monoclonal antibody, clone OTI5E2 (formerly 5E2), HRP conjugated 100 ul
TA502870S TP53 mouse monoclonal antibody, clone OTI5E2 (formerly 5E2) 30 ul

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