RR-11a [1361390-56-8]
Référence T12769-25mg
Conditionnement : 25mg
Marque : TargetMol
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RR-11a
Copy Product InfoRR-11a is a synthetic enzyme legumain inhibitor. This compound specifically targets and inhibits the activity of legumain, an enzyme implicated in various biological processes. RR-11a's synthetic nature allows for precise modulation of legumain activity, making it a valuable tool in biochemical research and potential therapeutic applications.
Cas No. 1361390-56-8
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | RR-11a is a synthetic enzyme legumain inhibitor. This compound specifically targets and inhibits the activity of legumain, an enzyme implicated in various biological processes. RR-11a's synthetic nature allows for precise modulation of legumain activity, making it a valuable tool in biochemical research and potential therapeutic applications. |
| Targets & IC50 | Legumain:31-55 nM (IC50) |
| In vitro | Legumain-targeted nanoparticles coupled with RR-11a demonstrate substantial ligand-receptor affinity, thereby enabling enhanced penetration and uptake within solid tumors by tumor cells. |
| In vivo | Tumor-bearing mice treated with RR-11a-coupled NPs encapsulating doxorubicin results in improved tumor selectivity and drug sensitivity, It completely inhibits tumor growth. |
| Molecular Weight | 560.51 |
| Formula | C24H28N6O10 |
| Cas No. | 1361390-56-8 |
| Smiles | O(C(/C=C/C(N(NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)C)=O)C)=O)CC(N)=O)=O)=O)N2C(=O)CCC2=O |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |