Sodium citrate [68-04-2]

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Référence T64923-1g

Conditionnement : 1g

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Sodium citrate

(Synonyms: Natrocitral, Citrosodine) Copy Product Info
Sodium citrate (Natrocitral) is the sodium salt of citric acid.Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Sodium citrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities.
Sodium citrate
Cas No. 68-04-2
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.90%
Appearance:Solid
Color:White
COA HNMR HPLC

Product Introduction

Bioactivity
Description
Sodium citrate (Natrocitral) is the sodium salt of citric acid.Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Sodium citrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities.
In vitro
Sodium citrate (12.5 mM; 72 h) induces apoptosis and cell cycle arrest at G2/M phase and S phase in a dosedependent manner. Citric acid trisodium (12.5 mM; 48 h) increases the expression of FAS, BAX, BID, AIF, EndoG, cytochrome c, PARP, GADD153, GRP78 and caspase-3, -8, -9, and decreases of BCL-2 and BCL-Xl [1].
In vivo
Sodium Citrate is the sodium salt of citrate with alkalinizing activity. Upon absorption, sodium citrate dissociates into sodium cations and citrate anions; organic citrate ions are metabolized to bicarbonate ions, resulting in an increase in the plasma bicarbonate concentration, the buffering of excess hydrogen ion, the raising of blood pH, and potentially the reversal of acidosis. In addition, increases in free sodium load due to sodium citrate administration may increase intravascular blood volume, facilitating the excretion of bicarbonate compounds and an anti-urolithic effect [2].
SynonymsNatrocitral, Citrosodine
Chemical Properties
Molecular Weight258.07
FormulaC6H5Na3O7
Cas No.68-04-2
SmilesC(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Na+].[Na+].[Na+]
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 105 mg/mL (406.87 mM), Sonication is recommended.
DMSO: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM3.8749 mL19.3746 mL38.7492 mL193.7459 mL
5 mM0.7750 mL3.8749 mL7.7498 mL38.7492 mL
10 mM0.3875 mL1.9375 mL3.8749 mL19.3746 mL
20 mM0.1937 mL0.9687 mL1.9375 mL9.6873 mL
50 mM0.0775 mL0.3875 mL0.7750 mL3.8749 mL
100 mM0.0387 mL0.1937 mL0.3875 mL1.9375 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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