SorLA Recombinant Antibody, PE-Cy7 Conjugated
Référence bsm-62077R-PE-Cy7
Conditionnement : 100uL
Marque : Bioss
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Applications
Reactivity
| Overview | |
| Catalog # | bsm-62077r-pe-cy7 |
| Product Name | SorLA Recombinant Antibody, PE-Cy7 Conjugated |
| Applications | WB |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | PE-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Sortilin related receptor |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 6653 |
| Swiss Prot | Q92673 |
| Subcellular location | Cell membrane |
| Synonyms | gp250; LR11; LRP9; SORL1; SorLA 1; SorLA. |
| Background | Sorting receptor that directs several proteins to their correct location within the cell (Probable). Along with AP-1 complex, involved Golgi apparatus - endosome sorting.Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. |
| Application Dilution | |
| WB | 1:300-5000 |