TCEB3 Antibody
Référence MBS8581891-0,1mL-PE
Conditionnement : 0.1mL(PE)
Marque : MyBiosource
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TCEB3 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8581891MBS8581891 is an antibody targeting TCEB3. Also known as TCEB3 Antibody. Reactive in Human, Rat, Monkey. Host: Rabbit. Rabbit polyclonal antibody to TCEB3 More details
Product Overview
Online Datasheet in PDFProduct Name
TCEB3, Polyclonal Antibody
Full Product Name
TCEB3 Antibody
Product Gene Name
anti-TCEB3 antibody
Product Synonym Names
Transcription elongation factor B polypeptide 3; Elongin 110 kDa subunit; Elongin-A; EloA; RNA polymerase II transcription factor SIII subunit A1; SIII p110
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of TCEB3 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
798
OMIM
600786
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TCEB3. The exact sequence is proprietary.
Product Categories/Family for anti-TCEB3 antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TCEB3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TCEB3 antibody
WB: 1:500-1:1000
IHC: 1:50-1:200
IHC: 1:50-1:200
Other Notes
Small volumes of anti-TCEB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for TCEB3. It may not necessarily be applicable to this product.
NCBI Official Full Name
Transcription elongation factor B polypeptide 3
NCBI Official Synonym Full Names
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
NCBI Official Symbol
TCEB3
NCBI Official Synonym Symbols
EloA; SIII; TCEB3A; SIII p110
UniProt Protein Name
Transcription elongation factor B polypeptide 3
UniProt Synonym Protein Names
Elongin 110 kDa subunit; Elongin-A; EloA; RNA polymerase II transcription factor SIII subunit A1; SIII p110
Protein Family
Transcription elongation factor B polypeptide
UniProt Gene Name
TCEB3
UniProt Synonym Gene Names
EloA
UniProt Entry Name
ELOA1_HUMAN
NCBI Protein Information
transcription elongation factor B polypeptide 3; elongin-A; elongin 110 kDa subunit; transcription elongation factor B alpha subunit; RNA polymerase II transcription factor SIII subunit A1
NCBI Summary for TCEB3
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for TCEB3
TCEB3: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Heterotrimer of an A (A1, A2 or A3), B and C subunit. The C subunit mediates the binding of the elongin BC complex to subunit A.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 1p36.1
Cellular Component: nucleoplasm; extracellular space; cytoplasm; integral to membrane; nucleus
Molecular Function: DNA binding
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; gene expression
Show more Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 1p36.1
Cellular Component: nucleoplasm; extracellular space; cytoplasm; integral to membrane; nucleus
Molecular Function: DNA binding
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; gene expression
Research Articles on TCEB3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-TCEB3 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Disease Pathway antibodies | Disease Pathway Diagram |
| Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway antibodies | Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway Diagram |
| Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies | Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram |
| Formation Of RNA Pol II Elongation Complex Pathway antibodies | Formation Of RNA Pol II Elongation Complex Pathway Diagram |
| Gene Expression Pathway antibodies | Gene Expression Pathway Diagram |
| HIV Infection Pathway antibodies | HIV Infection Pathway Diagram |
| HIV Life Cycle Pathway antibodies | HIV Life Cycle Pathway Diagram |
| HIV Transcription Elongation Pathway antibodies | HIV Transcription Elongation Pathway Diagram |
| HIV Elongation Arrest And Recovery Pathway antibodies | HIV Elongation Arrest And Recovery Pathway Diagram |
| Late Phase Of HIV Life Cycle Pathway antibodies | Late Phase Of HIV Life Cycle Pathway Diagram |
Organs/Tissues associated with anti-TCEB3 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >1 publications with TCEB3 and Blood |
| Testis Antibodies | >1 publications with TCEB3 and Testis |