TUFM Polyclonal Antibody
Référence MBS2534914-0,06mL
Conditionnement : 0.06mL
Marque : MyBiosource
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Immunohistochemistry of paraffin-embedded Human esophageal cancer using TUFM Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of MCF7 cells using TUFM Polyclonal Antibody
Confocal immunofluorescence analysis of U2OS cells using TUFM Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
TUFM Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2534914This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been… More details
Product Overview
Online Datasheet in PDFProduct Name
TUFM, Polyclonal Antibody
Full Product Name
TUFM Polyclonal Antibody
Product Gene Name
anti-TUFM antibody
Product Synonym Names
TUFM; COXPD4; EF-TuMT; EFTU; P43
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
Applications Tested/Suitable for anti-TUFM antibody
Immunohistochemistry (IHC), Immunofluoresence (IF)
Application Notes for anti-TUFM antibody
IHC: 1:50-1:200
IF: 1:10-1:100
IF: 1:10-1:100
Other Notes
Small volumes of anti-TUFM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for TUFM purchase
MBS2534914 is an antibody targeting TUFM. Also known as TUFM Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for TUFM. It may not necessarily be applicable to this product.
NCBI Official Full Name
TUFM, partial
NCBI Official Synonym Full Names
Tu translation elongation factor, mitochondrial
NCBI Official Symbol
TUFM
NCBI Official Synonym Symbols
P43; EFTU; COXPD4; EF-TuMT
UniProt Protein Name
Elongation factor Tu, mitochondrial
UniProt Synonym Protein Names
P43
UniProt Gene Name
TUFM
UniProt Synonym Gene Names
EF-Tu
UniProt Entry Name
EFTU_HUMAN
NCBI Protein Information
elongation factor Tu, mitochondrial
UniProt Comments for TUFM
EFTU: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Defects in TUFM are the cause of combined oxidative phosphorylation deficiency type 4 (COXPD4). COXPD4 is characterized by neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes. Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.
Protein type: Mitochondrial; RNA-binding; Translation elongation; Translation
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: membrane; mitochondrion
Molecular Function: GTP binding; GTPase activity; protein binding; translation elongation factor activity
Biological Process: mitochondrial translation; organelle organization and biogenesis; translational elongation
Disease: Combined Oxidative Phosphorylation Deficiency 4
Show more Protein type: Mitochondrial; RNA-binding; Translation elongation; Translation
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: membrane; mitochondrion
Molecular Function: GTP binding; GTPase activity; protein binding; translation elongation factor activity
Biological Process: mitochondrial translation; organelle organization and biogenesis; translational elongation
Disease: Combined Oxidative Phosphorylation Deficiency 4
Research Articles on TUFM
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-TUFM antibody
| Reference Product | PubMed Publications |
|---|---|
| TSFM antibody | >2 publications with TUFM and TSFM |
| RPS15A antibody | >1 publications with TUFM and RPS15A |
| UBC antibody | >1 publications with TUFM and UBC |
Pathways associated with anti-TUFM antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Mitochondrial Translation Pathway antibodies | Mitochondrial Translation Pathway Diagram |
| Mitochondrial Translation Elongation Pathway antibodies | Mitochondrial Translation Elongation Pathway Diagram |
| Organelle Biogenesis And Maintenance Pathway antibodies | Organelle Biogenesis And Maintenance Pathway Diagram |
Diseases associated with anti-TUFM antibody
| Disease Name | Pubmed Publications |
|---|---|
| Brain Diseases Antibodies | >4 publications with TUFM and Brain Diseases |
| Nervous System Diseases Antibodies | >4 publications with TUFM and Nervous System Diseases |
| Inflammation Antibodies | >3 publications with TUFM and Inflammation |
| Liver Neoplasms Antibodies | >2 publications with TUFM and Liver Neoplasms |
| Liver Diseases Antibodies | >1 publications with TUFM and Liver Diseases |
| Heart Diseases Antibodies | >1 publications with TUFM and Heart Diseases |
| Necrosis Antibodies | >1 publications with TUFM and Necrosis |
Organs/Tissues associated with anti-TUFM antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >11 publications with TUFM and Blood |
| Muscle Antibodies | >7 publications with TUFM and Muscle |
| Lung Antibodies | >6 publications with TUFM and Lung |
| Brain Antibodies | >6 publications with TUFM and Brain |
| Liver Antibodies | >5 publications with TUFM and Liver |
| Heart Antibodies | >4 publications with TUFM and Heart |
| Lymph Antibodies | >2 publications with TUFM and Lymph |
| Eye Antibodies | >2 publications with TUFM and Eye |
| Placenta Antibodies | >2 publications with TUFM and Placenta |
| Skin Antibodies | >2 publications with TUFM and Skin |