HP Detection Antibody
Référence OAOA22235
Conditionnement : 50µg
Marque : Aviva Systems Biology
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HP Detection Antibody : Biotin (OAOA22235)
| Datasheets/Manuals | Printable datasheet for HP Detection Antibody : Biotin (OAOA22235) |
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| Predicted Species Reactivity | Human |
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| Product Format | Stored in PBS (pH 7.4) with 0.05% sodium azide, 10mg/ml BSA, 50% glycerol |
| Clonality | Monoclonal |
| Clone | OTI6H2 |
| Isotype | IgG1 |
| Host | Mouse |
| Conjugation | Biotin |
| Application | ELISA |
| Additional Information | Matched ELISA Pair: OAOA21798 |
| Reconstitution and Storage | -20°C |
| Immunogen | Full length human recombinant protein of human HP (NM_005143) produced in HEK293T cell. |
| Concentration | 0.5 mg/ml |
| Description | HP biotinylated mouse monoclonal detection antibody, validated for Luminex assays |
| Gene Symbol | HP |
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| Gene Full Name | haptoglobin |
| Alias Symbols | binding peptide, BP, haptoglobin, haptoglobin alpha(1S)-beta, haptoglobin alpha(2FS)-beta, haptoglobin, alpha polypeptide, haptoglobin, beta polypeptide, HP2ALPHA2, HPA1S, zonulin. |
| NCBI Gene Id | 3240 |
| Protein Name | Haptoglobin|Homo sapiens haptoglobin (HP), transcript variant 1, mRNA |
| Description of Target | As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. |
| Uniprot ID | P00738 |
| Protein Accession # | NP_005134 |
| Nucleotide Accession # | https://www.ncbi.nlm.nih.gov/nuccore/NM_005143 |
