HP Detection Antibody

Cat# OAOA22235

Size : 50µg

Brand : Aviva Systems Biology

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Phone : +1 850 650 7790

Datasheets/ManualsPrintable datasheet for HP Detection Antibody : Biotin (OAOA22235)
Product Info
Predicted Species ReactivityHuman
Product FormatStored in PBS (pH 7.4) with 0.05% sodium azide, 10mg/ml BSA, 50% glycerol
ClonalityMonoclonal
CloneOTI6H2
IsotypeIgG1
HostMouse
ConjugationBiotin
ApplicationELISA
Additional InformationMatched ELISA Pair: OAOA21798
Reconstitution and Storage-20°C
ImmunogenFull length human recombinant protein of human HP (NM_005143) produced in HEK293T cell.
Concentration0.5 mg/ml
DescriptionHP biotinylated mouse monoclonal detection antibody, validated for Luminex assays
Gene SymbolHP
Gene Full Namehaptoglobin
Alias Symbolsbinding peptide, BP, haptoglobin, haptoglobin alpha(1S)-beta, haptoglobin alpha(2FS)-beta, haptoglobin, alpha polypeptide, haptoglobin, beta polypeptide, HP2ALPHA2, HPA1S, zonulin.
NCBI Gene Id3240
Protein NameHaptoglobin|Homo sapiens haptoglobin (HP), transcript variant 1, mRNA
Description of TargetAs a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
Uniprot IDP00738
Protein Accession #NP_005134
Nucleotide Accession #https://www.ncbi.nlm.nih.gov/nuccore/NM_005143