SK00170-08 | Irisin (Human) ELISA Kit Biovalley

Description

Technical Specs

More Information:

Irisin, a secreted myokine, is a circulating biomarker for metabolic syndrome. This new Irisin Elisa kit was formulated by the glycosylated human irisin derived from HEK293 cells and specific monoclonal antibody. The antibody was validated by the glycosylated human irisin derived from HEK293 cells and human serum samples on western blot.

Citations:

Gonzalez-Gil AM, et al. Myokine-adipokine cross-talk: potential mechanisms for the association between plasma irisin and adipokines and cardiometabolic risk factors in Mexican children with obesity and the metabolic syndrome. Diabetol Metab Syndr. 2019 Aug 5;11:63. doi: 10.1186/s13098-019-0458-2. eCollection 2019
Anna S. Huerta-Delgado, et al, "Serum Irisin Levels, Endothelial Dysfunction, and Inflammation in Pediatric Patients with Type 2 Diabetes Mellitus and Metabolic Syndrome", Journal of Diabetes Research, vol. 2020, Article ID 1949415, 16 pages, 2020.
Śliwicka E, et al. Effects of marathon race on selected myokines and sclerostin in middle-aged male amateur runners. Sci Rep. 2021 Feb 2;11(1):2813.

Ewa Śliwicka et al. "Serum irisin and myostatin levels after 2 weeks of high-altitude climbing" https://doi.org/10.1371/journal.pone.0181259

Dr. Zhu Li, et al. The relationship between circulating irisin levels and tissues AGE accumulation in type 2 diabetes patients. Biosci Rep. 2017 Jun 30; 37(3) :BSR20170213 https://journals.lww.com/mdjournal/Fulltext/2018/04270/Serum_irisin_associates_with_breast_cancer_to.55.aspx#pdf-link

Anna S. Huerta-Delgado., et al. "Serum Irisin Levels..." ", Journal of Dia--betes Research, vol. 2020, Article ID 1949415, 16 pages, 2020. https://doi.org/10.1155/2020/1949415

Dr. Zheng-ping Zhang, et al. Serum irisin associated with breast cancer to spinal metastasis. Medicine (2018) 97:17 http://dx.doi.org/10.1097/MD.0000000000010524
Zhang, Feng et al. “Serum Irisin as a Potential Biomarker for Cognitive Decline in Vascular Dementia.” Frontiers in neurology vol. 12 755046. 13 Sep. 2021, doi:10.3389/fneur.2021.755046

New Research:

Eunhee Kim, et al. Irisin reduces amyloid-b by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling. Neuron 111, 3619–3633, November 15, 2023.
Jo D, Song J. Irisin Acts via the PGC-1α and BDNF Pathway to Improve Depression-like Behavior. Clin Nutr Res. 2021 Oct 20;10(4):292-302. PMID: 34796134; PMCID: PMC8575642.

Features

Irisin (Human) ELISA Kit
Code: SK00170-08
Size: 96 T
Standard Range: 0.2 - 12.8 ng/ml
Sensitivity: 50 pg/ml
Specificity: Human
Calibration: human Irisin derived from human cells
Sample Type: serum, plasma
Dilution Factor: 8~32
Sample Requires: 100 ul per well
Intra-CV: 4-6%
Inter-CV: 4-9%
Protocol: PDF
Monoclonal Antibody was validated by human Irisin derived HEK293 cells on WB

Irisin (Human) ELISA Kit

Référence SK00170-08

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Marque : Aviscera Bioscience

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