Rosnilimab [2412764-40-8]
Référence T80619-1mg
Conditionnement : 1mg
Marque : TargetMol
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Rosnilimab
(Synonyms: ANB-030, ANB030) Copy Product InfoRosnilimab (ANB030) is a programmed cell death protein 1 (PD-1) agonist that can inhibit antigen-driven T cell proliferation, reduce the secretion of pro-inflammatory cytokines, and deplete CD4 and CD8 T cell populations characterized by high PD-1 expression, thereby enabling its use in the research of various inflammatory diseases such as colitis and rheumatoid arthritis.
Cas No. 2412764-40-8
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.9% (SDS-PAGE); 98.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
COA SDS-PAGE SEC-HPLC Instruction Manual of Inhibitory Antibody
Product Information
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Rosnilimab (ANB030) is a programmed cell death protein 1 (PD-1) agonist that can inhibit antigen-driven T cell proliferation, reduce the secretion of pro-inflammatory cytokines, and deplete CD4 and CD8 T cell populations characterized by high PD-1 expression, thereby enabling its use in the research of various inflammatory diseases such as colitis and rheumatoid arthritis. |
| Synonyms | ANB-030, ANB030 |
| Reactivity | Human |
| Verified Activity | Immobilized Human PD-1 Protein (His) (TMPY-00897) at 1 μg/mL (100 μL/well) can bind Rosnilimab. The EC50 is 6.00 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | 5133 |
| Uniprot ID | Q15116 |
| Target | PDCD1/PD-1/CD279 |
| Molecular Weight | 146.57 kDa (Predicted) |
| Cas No. | 2412764-40-8 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control | Human IgG1 kappa, Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |