Cell Culture contamination control

Cell Culture contamination control

 

Mycoplasma contamination represents a major concern for academic (e.g. cell biology) or biopharmaceutical (production of vaccines, monoclonal antibodies etc.) facilities.
 
Mycoplasmas are the smallest self-propagating microorganisms and can reproduce in the extracellular space. While mostly harmless in humans, other animal hosts, and plants, some species can cause human diseases. In particular, 6 species represent a frequent cause of contamination in continuous cell lines and primary cells. Due to their size, mycoplasmas evade detection (e.g. microscopy) and yet profoundly alter cell cultures (metabolism, cell growth, pH, viability, membrane transport).
The main source of mycoplasma contaminations are other infected cell cultures as well as culture media, reagents (fetal bovine serum, trypsin, etc.) and laboratory personnel.
 
Mycoplasma contaminations can cost money, time, and reputation, undermine research findings or impact safety of biological therapeutics. Successful strategies against mycoplasma contaminations are prevention, early detection, disposal of infected materials or mycoplasma elimination.

 


Frequently Asked Questions (FAQ)

Where can I find contamination control products on the Biovalley website?

contamination control products are available in this section and can be sorted by product families or sub-categories, such as Detection, Prevention, Elimination. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.

What types of products are available in the contamination control category?

The contamination control category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The Detection, Prevention, Elimination sub-categories allow you to find the products that meet your needs more quickly.

How can I quickly find a contamination control product?

To find a contamination control product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does Biovalley stock several product codes in the contamination control category?

Yes, Biovalley distributes several product references in the contamination control category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for contamination control products?

Yes, you can request a quote for contamination control products from the product page or by contacting Biovalley (info@biovalley.fr). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a contamination control product is available to order?

The availability of a contamination control product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Biovalley with the product code or name of the product you are looking for.

What should I do if I cannot find the contamination control product I am looking for?

If the contamination control product you are looking for does not appear in the catalogue, please contact Biovalley with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all contamination control products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.