New MI PathArray™ assays focus on research area-specific pathways in development and disease, bringing the highest microarray sensitivity to your research. Gene expression analysis is often performed using whole-genome microarrays resulting in very large data sets that generate information irrelevant to the focused researcher. Alternative methods for focused gene expression currently utilize qPCR, but these tools have limited gene coverage due to high assay costs and limited instrument capabilities. The MI PathArray microarray platform provides an alternative : a focused gene pathway tool with current scientifically-relevant gene content providing manageable data sets for focused analysis in a cost-effective multi-assay platform.

Each multi-assay slide includes four discrete, identical arrays containing pathway-specific collection of 70mer oligonucleotides selected through a vigorous curation process from the MI collection of human gene probes. Probes and controls are printed in triplicate in each assay area offering increased sensitivity and statistical power. Control probes for every assay include 17 probes for widely expressed genes (positive controls), 6 negative probes, and a series of 8 probes for use with spike-in controls used to determine the limits of detectability.