ABCA12 Antibody

Cat# MBS9609561-0,1mL

Size : 0.1mL

Brand : MyBiosource

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ABCA12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9609561

Function: Probable transporter involved in lipid homeostasis.Similarity: Multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain. Belongs to the ABC transporter… More details

Product Overview

Online Datasheet in PDF
Product Name
ABCA12, Polyclonal Antibody
Full Product Name
ABCA12 Antibody
Product Gene Name
anti-ABCA12 antibody
Product Synonym Names
ABC transporter A family member 12; ABC transporter ABCA.12; ABC12; ABCA12; ABCAC_HUMAN; AtABCA12; ATH16; ATP binding cassette 12; ATP binding cassette sub family A (ABC1) member 12; ATP binding cassette sub family A member 12; ATP binding cassette transporter 12; ATP-binding cassette 12; ATP-binding cassette sub-family A member 12; ATP-binding cassette transporter 12; Ichthyosis congenita II lamellar ichthyosis B; ICR2B; LI2; Putative ABC2 homolog 16
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Concentration
~1mg/ml (lot specific)
Specificity
ABCA12 antibody detects endogenous levels of total ABCA12
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Antibody/Peptide Pairs
ABCA12 peptide (MBS9628265) is used for blocking the activity of ABCA12 antibody (MBS9609561)
Molecular Weight
Observed: 293 kDa
Predicted: 294 kDa
3D Structure
ModBase 3D Structure for Q86UK0
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Immunogen
A synthesized peptide derived from human ABCA12, corresponding to a region within C-terminal amino acids.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ABCA12 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ABCA12 antibody
WB: 1:1000-3000
ELISA (peptide): 1:20000-1:40000
The optimal dilution should be determined by the end user.
IMPORTANT: For western blots, incubate membrane with diluted antibody in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4°C with gentle shaking, overnight.

Western Blot (WB) of anti-ABCA12 antibody

Western blot analysis of extracts from DU145 cells, using ABCA12 Ab. The lane on the left was treated with blocking peptide
Rabbit Anti-ABCA12 Polyclonal Antibody – Cat# MBS9609561

Other Notes

Small volumes of anti-ABCA12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABCA12 purchase

MBS9609561 is an antibody targeting ABCA12. Also known as ABCA12 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ABCA12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ATP-binding cassette sub-family A member 12 isoform b
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 12
NCBI Official Symbol
ABCA12
NCBI Official Synonym Symbols
LI2; ICR2B; ARCI4A; ARCI4B
UniProt Protein Name
ATP-binding cassette sub-family A member 12
UniProt Synonym Protein Names
ATP-binding cassette transporter 12; ATP-binding cassette 12
Protein Family
ABC transporter A family
UniProt Gene Name
ABCA12
UniProt Synonym Gene Names
ABC12; ATP-binding cassette 12
NCBI Protein Information
ATP-binding cassette sub-family A member 12

NCBI Summary for ABCA12

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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UniProt Comments for ABCA12

Probable transporter involved in lipid homeostasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ABCA12 antibody

 Reference Product  PubMed Publications
 TGM1 antibody  >6 publications with ABCA12 and TGM1
 ALOXE3 antibody  >6 publications with ABCA12 and ALOXE3
 CYP4F22 antibody  >4 publications with ABCA12 and CYP4F22
 NIPAL4 antibody  >3 publications with ABCA12 and NIPAL4
 LOR antibody  >1 publications with ABCA12 and LOR
 FLG antibody  >1 publications with ABCA12 and FLG
 ABCC13 antibody  >1 publications with ABCA12 and ABCC13

Pathways associated with anti-ABCA12 antibody

 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 ABCA Transporters In Lipid Homeostasis Pathway antibodies  ABCA Transporters In Lipid Homeostasis Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with anti-ABCA12 antibody

 Disease Name  Pubmed Publications
 Ichthyosis, Lamellar Antibodies  >61 publications with ABCA12 and Ichthyosis, Lamellar
 Congenital Abnormalities Antibodies  >56 publications with ABCA12 and Congenital Abnormalities
 Inflammation Antibodies  >4 publications with ABCA12 and Inflammation
 Atherosclerosis Antibodies  >4 publications with ABCA12 and Atherosclerosis
 Skin Neoplasms Antibodies  >2 publications with ABCA12 and Skin Neoplasms
 Carcinoma, Squamous Cell Antibodies  >2 publications with ABCA12 and Carcinoma, Squamous Cell
 Breast Neoplasms Antibodies  >2 publications with ABCA12 and Breast Neoplasms
 Lamellar ichthyosis, type 2 Antibodies  >2 publications with ABCA12 and Lamellar ichthyosis, type 2
 Immune System Diseases Antibodies  >2 publications with ABCA12 and Immune System Diseases
 Fibrosis Antibodies  >1 publications with ABCA12 and Fibrosis

Organs/Tissues associated with anti-ABCA12 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >39 publications with ABCA12 and Skin
 Lung Antibodies  >4 publications with ABCA12 and Lung
 Mouth Antibodies  >2 publications with ABCA12 and Mouth
 Brain Antibodies  >2 publications with ABCA12 and Brain
 Placenta Antibodies  >1 publications with ABCA12 and Placenta

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