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> Aldehyde Dehydrogenase Microplate Assay Kit

Aldehyde Dehydrogenase Microplate Assay Kit

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Cat# MBS8243237-5x100

Size : 5x100Assays

Brand : MyBiosource

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Aldehyde Dehydrogenase (ALDH3A2) Assay Kit for General

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8243237

Background: In mammals, ethanol is metabolized mainly in the liver by alcohol dehydrogenase (ADH), which oxidizes ethanol to acetaldehyde. Acetaldehyde, a toxic metabolite responsible for the miserable effects of hangovers, is further oxidized to acetate by… More details

Product Overview

Online Datasheet in PDF
Product Name
Aldehyde Dehydrogenase (Aldh3a2), Assay Kit
Full Product Name
Aldehyde Dehydrogenase Microplate Assay Kit
Product Gene Name
Aldh3a2 assay kit
Product Synonym Names
EC 1.2.1.3; Aldehyde dehydrogenase (NAD(+))
Species Reactivity
General
Samples
Urine, Serum, Plasma, Tissue extracts, Cell lysate, Cell culture media and Other biological fluids Samples
Detection Range
4 umol/L - 400 umol/L
Preparation and Storage
Shipped and store at 4 degree C for 6 months.
Molecular Weight
54,082 Da
Applications Tested/Suitable for Aldh3a2 assay kit
Functional Assay

Typical Testing Data/Standard Curve (for reference only) of Aldh3a2 assay kit

General ALDH3A2 Assay Kit – Cat# MBS8243237

Other Notes

Small volumes of Aldh3a2 assay kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Aldh3a2 purchase

MBS8243237 is an assay kit targeting Aldh3a2. Also known as Aldehyde Dehydrogenase Microplate Assay Kit. Reactive in General.

Additional Details

NCBI/Uniprot data below describe general gene information for Aldh3a2. It may not necessarily be applicable to this product.

NCBI GI #
205266
NCBI GeneID
65183
NCBI Accession #
AAA41555.1
UniProt Related Accession #
P30839
NCBI Official Full Name
aldehyde dehydrogenase
NCBI Official Synonym Full Names
aldehyde dehydrogenase 3 family, member A2
NCBI Official Symbol
Aldh3a2
NCBI Official Synonym Symbols
Aldh4; FALDH
UniProt Protein Name
Fatty aldehyde dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A2; Microsomal aldehyde dehydrogenase; msALDH
Protein Family
Fatty aldehyde dehydrogenase
UniProt Gene Name
Aldh3a2
UniProt Synonym Gene Names
Aldh4; msALDH
UniProt Entry Name
AL3A2_RAT
NCBI Protein Information
fatty aldehyde dehydrogenase

UniProt Comments for Aldh3a2

ALDH3A2: Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. Defects in ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS). SLS is an autosomal recessive neurocutaneous disorder characterized by a combination of severe mental retardation, spastic di- or tetraplegia and congenital ichthyosis (increased keratinization). Ichthyosis is usually evident at birth, neurologic symptoms appear in the first or second year of life. Most patients have an IQ of less than 60. Additional clinical features include glistening white spots on the retina, seizures, short stature and speech defects. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Mitochondrial; Oxidoreductase; Membrane protein, integral; Amino Acid Metabolism - lysine degradation; Carbohydrate Metabolism - butanoate; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - ascorbate and aldarate; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 1.2.1.3; Amino Acid Metabolism - histidine; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - propanoate; Lipid Metabolism - fatty acid

Cellular Component: cytosol; endoplasmic reticulum; integral to membrane; intracellular membrane-bound organelle; mitochondrial inner membrane; mitochondrion; nucleus; peroxisome

Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; long-chain-alcohol oxidase activity; long-chain-aldehyde dehydrogenase activity

Biological Process: aldehyde metabolic process; central nervous system development; epidermis development; formaldehyde metabolic process; peripheral nervous system development; phytol metabolic process; response to reactive oxygen species; sesquiterpenoid metabolic process
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Research Articles on Aldh3a2

1. FALDH has roles in insulin action and is deregulated in states associated with altered insulin signaling

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Aldh3a2 assay kit

 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway antibodies  GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway Diagram
 GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway antibodies  GABA Biosynthesis, Eukaryotes, Putrescine => GABA Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram

Diseases associated with Aldh3a2 assay kit

 Disease Name  Pubmed Publications
 Sjogren-Larsson Syndrome Antibodies  >32 publications with Aldh3a2 and Sjogren-Larsson Syndrome
 Fatty Liver Antibodies  >2 publications with Aldh3a2 and Fatty Liver
 Infertility, Male Antibodies  >1 publications with Aldh3a2 and Infertility, Male
 Neoplasms, Experimental Antibodies  >1 publications with Aldh3a2 and Neoplasms, Experimental
 Weight Loss Antibodies  >1 publications with Aldh3a2 and Weight Loss
 Hyperplasia Antibodies  >1 publications with Aldh3a2 and Hyperplasia

Organs/Tissues associated with Aldh3a2 assay kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with Aldh3a2 and Brain
 Liver Antibodies  >5 publications with Aldh3a2 and Liver
 Spleen Antibodies  >1 publications with Aldh3a2 and Spleen
 Connective Tissue Antibodies  >1 publications with Aldh3a2 and Connective Tissue