Anti-CD52 [YTH 34.5-G2b (Campath-1G)]
Cat# MBS488133-0,2mg
Size : 0.2mg
Brand : MyBiosource
CD52 Recombinant Antibody
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS488133Recombinant monoclonal antibody to CD52. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the hybridoma YTH 34.5-G2b (Campath-1G). This is a chimeric mouse antibody, based on the original rat IgG2b format, created for… More details
Product Overview
Online Datasheet in PDFProduct Name
CD52, Recombinant Antibody
Full Product Name
Anti-CD52 [YTH 34.5-G2b (Campath-1G)]
Product Gene Name
CD52 recombinant antibody
Product Synonym Names
CDw52; Cambridge pathology 1 antigen; Epididymal secretory protein E5; Human epididymis-specific protein 5
Isotype
Mouse IgG1, kappa
Clone Number
YTH 34.5-G2b (Campath-1G)
Species Reactivity
Human, Rhesus Monkey
Purity/Purification
Protein A Affinity Purified
Specificity
Human CD52 antigen, also known as CAMPATH-1. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Molecular Weight
6,614 Da
OMIM
X62466 mRNA
Animal-free Manufacturing Platform
The recombinant antibody is manufactured using a recombinant, mammalian HEK293-based expression platform. The manufacturing platform is animal-free and animal component-free.
Buffer Composition
PBS only with 0.02% Proclin 300.
Immunogen
Human peripheral mononuclear cells enriched for T-cells.
Chimeric Use Statement
This is a chimeric mouse antibody, based on the original rat IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
Product Categories/Family for CD52 recombinant antibody
Invivo; Biotherapeutics; Biosimilar
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for CD52 recombinant antibody
Cytotoxicity Assay, ELISA (EIA), Immunohistochemistry (IHC) Formalin/Paraffin, In Vivo, Flow Cytometry (FC/FACS), Western Blot (WB)
Product References and Citations for CD52 recombinant antibody
Hale G et al. Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement. Blood. 1983 Oct; 62(4):873-82. PMID:6349718
Other Notes
Small volumes of CD52 recombinant antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CD52 purchase
MBS488133 is a recombinant antibody targeting CD52. Also known as Anti-CD52 [YTH 34.5-G2b (Campath-1G)]. Reactive in Human, Rhesus Monkey.
Additional Details
NCBI/Uniprot data below describe general gene information for CD52. It may not necessarily be applicable to this product.
NCBI Official Full Name
CAMPATH-1 antigen
NCBI Official Synonym Full Names
CD52 molecule
NCBI Official Symbol
CD52
NCBI Official Synonym Symbols
CDW52
UniProt Protein Name
CAMPATH-1 antigen
UniProt Synonym Protein Names
CDw52; Cambridge pathology 1 antigen; Epididymal secretory protein E5; Human epididymis-specific protein 5; He5; CD_antigen: CD52
Protein Family
CAMPATH-1 antigen
UniProt Gene Name
CD52
UniProt Synonym Gene Names
CDW52; HE5; He5
UniProt Entry Name
CD52_HUMAN
NCBI Protein Information
CAMPATH-1 antigen
UniProt Comments for CD52
CD52: May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
Protein type: Membrane protein, GPI anchor; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: integral to plasma membrane; membrane
Biological Process: elevation of cytosolic calcium ion concentration
Show more Protein type: Membrane protein, GPI anchor; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: integral to plasma membrane; membrane
Biological Process: elevation of cytosolic calcium ion concentration
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with CD52 recombinant antibody
| Reference Product | PubMed Publications |
|---|---|
| CD4 recombinant antibody | >103 publications with CD52 and CD4 |
| CD19 recombinant antibody | >55 publications with CD52 and CD19 |
| CD22 recombinant antibody | >38 publications with CD52 and CD22 |
| CD5 recombinant antibody | >27 publications with CD52 and CD5 |
| CD7 recombinant antibody | >8 publications with CD52 and CD7 |
| NPC2 recombinant antibody | >5 publications with CD52 and NPC2 |
| CRISP1 recombinant antibody | >2 publications with CD52 and CRISP1 |
| GPR64 recombinant antibody | >2 publications with CD52 and GPR64 |
Pathways associated with CD52 recombinant antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Metabolism Of Proteins Pathway antibodies | Metabolism Of Proteins Pathway Diagram |
| Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies | Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram |
| Post-translational Protein Modification Pathway antibodies | Post-translational Protein Modification Pathway Diagram |
Diseases associated with CD52 recombinant antibody
| Disease Name | Pubmed Publications |
|---|---|
| Cardiovascular Diseases Antibodies | >44 publications with CD52 and Cardiovascular Diseases |
| Thrombocytopenia Antibodies | >37 publications with CD52 and Thrombocytopenia |
| Inflammation Antibodies | >34 publications with CD52 and Inflammation |
| Necrosis Antibodies | >33 publications with CD52 and Necrosis |
| Infertility, Male Antibodies | >19 publications with CD52 and Infertility, Male |
| Lung Diseases Antibodies | >18 publications with CD52 and Lung Diseases |
| Kidney Diseases Antibodies | >16 publications with CD52 and Kidney Diseases |
| Disease Models, Animal Antibodies | >13 publications with CD52 and Disease Models, Animal |
| Liver Diseases Antibodies | >12 publications with CD52 and Liver Diseases |
| Neoplasms, Experimental Antibodies | >5 publications with CD52 and Neoplasms, Experimental |
Organs/Tissues associated with CD52 recombinant antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >415 publications with CD52 and Blood |
| Bone Marrow Antibodies | >146 publications with CD52 and Bone Marrow |
| Kidney Antibodies | >67 publications with CD52 and Kidney |
| Epididymis Antibodies | >37 publications with CD52 and Epididymis |
| Lymph Node Antibodies | >24 publications with CD52 and Lymph Node |
| Lymph Antibodies | >24 publications with CD52 and Lymph |
| Lung Antibodies | >21 publications with CD52 and Lung |
| Spleen Antibodies | >19 publications with CD52 and Spleen |
| Heart Antibodies | >17 publications with CD52 and Heart |
| Brain Antibodies | >17 publications with CD52 and Brain |


