General Information
| Short Description | Rabbit polyclonal anti-AMSH-like protease for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen | Synthesized peptide derived from human STAMBPL1 |
| Specificity | This antibody detects endogenous levels of STAMBPL1 at Human, Mouse |
Additional Info
| Function | Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex. Does not cleave 'Lys-48'-linked polyubiquitin chains. |
| Protein Name | Amsh-Like ProteaseAmsh-LpStam-Binding Protein-Like 1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Amsh-Like Protease antibodyAnti-Amsh-Lp antibodyAnti-Stam-Binding Protein-Like 1 antibodyAnti-STAMBPL1 antibodyAnti-AMSHLP antibodyAnti-KIAA1373 antibody |
Information sourced from Uniprot.org