Biotin-Linked Polyclonal Antibody to Transferrin Receptor (TFR)
Cat# MBS2092943-0,2mL
Size : 0.2mL
Brand : MyBiosource
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Transferrin Receptor (TFR) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2092943SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2092943 is an antibody targeting TFR. Also known as Biotin-Linked Polyclonal Antibody to Transferrin Receptor (TFR). Reactive in Chicken. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Transferrin Receptor (TFR), Polyclonal Antibody
Full Product Name
Biotin-Linked Polyclonal Antibody to Transferrin Receptor (TFR)
Product Gene Name
anti-TFR antibody
Product Synonym Names
CD71; TFR1; P90; TFRC; T9; Trfr; sTfR; Transferrin receptor protein 1, serum form
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Chicken
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: TFR (MBS2026361)
Biotin Conjugated Antibody: TFR (MBS2092943)
Biotin Conjugated Antibody: TFR (MBS2092943)
Matching Pairs
Biotin Conjugated Antibody: TFR (MBS2092943)
Immunogen: TFR (MBS2010017)
Immunogen: TFR (MBS2010017)
Molecular Weight
84,871 Da
OMIM
X01060 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
Biotin
Cross Reactivity
Chicken
Immunogen
TFR (Thr585~Lys771)
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-TFR antibody
Western Blot (WB)
Other Notes
Small volumes of anti-TFR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for TFR. It may not necessarily be applicable to this product.
NCBI Official Full Name
transferrin receptor
NCBI Official Synonym Full Names
transferrin receptor
NCBI Official Symbol
TFRC
NCBI Official Synonym Symbols
T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
UniProt Protein Name
Transferrin receptor protein 1
UniProt Synonym Protein Names
T9; p90; CD_antigen: CD71
UniProt Gene Name
TFRC
UniProt Synonym Gene Names
TR; TfR; TfR1; Trfr; sTfR
NCBI Protein Information
transferrin receptor protein 1
NCBI Summary for TFR
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
UniProt Comments for TFR
TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.
Protein type: Cell surface; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: basolateral plasma membrane; blood microparticle; cell surface; clathrin-coated pit; clathrin-coated vesicle membrane; cytoplasmic vesicle; early endosome; endosome; endosome membrane; external side of plasma membrane; extracellular exosome; extracellular region; extracellular space; HFE-transferrin receptor complex; integral component of plasma membrane; melanosome; membrane; perinuclear region of cytoplasm; plasma membrane; recycling endosome
Molecular Function: double-stranded RNA binding; identical protein binding; protein binding; protein homodimerization activity; RNA binding; transferrin receptor activity; transferrin transmembrane transporter activity; viral receptor activity
Biological Process: cellular iron ion homeostasis; entry of virus into host cell; osteoclast differentiation; positive regulation of B cell proliferation; positive regulation of bone resorption; positive regulation of isotype switching; positive regulation of T cell proliferation; receptor internalization; regulation of cell growth; regulation of cell proliferation; transferrin transport
Disease: Immunodeficiency 46
Show more Protein type: Cell surface; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: basolateral plasma membrane; blood microparticle; cell surface; clathrin-coated pit; clathrin-coated vesicle membrane; cytoplasmic vesicle; early endosome; endosome; endosome membrane; external side of plasma membrane; extracellular exosome; extracellular region; extracellular space; HFE-transferrin receptor complex; integral component of plasma membrane; melanosome; membrane; perinuclear region of cytoplasm; plasma membrane; recycling endosome
Molecular Function: double-stranded RNA binding; identical protein binding; protein binding; protein homodimerization activity; RNA binding; transferrin receptor activity; transferrin transmembrane transporter activity; viral receptor activity
Biological Process: cellular iron ion homeostasis; entry of virus into host cell; osteoclast differentiation; positive regulation of B cell proliferation; positive regulation of bone resorption; positive regulation of isotype switching; positive regulation of T cell proliferation; receptor internalization; regulation of cell growth; regulation of cell proliferation; transferrin transport
Disease: Immunodeficiency 46
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-TFR antibody
| Reference Product | PubMed Publications |
|---|---|
| HFE antibody | >18 publications with TFR and HFE |
| MYC antibody | >13 publications with TFR and MYC |
| B2M antibody | >8 publications with TFR and B2M |
| EPO antibody | >4 publications with TFR and EPO |
| STEAP3 antibody | >1 publications with TFR and STEAP3 |
| FTH1 antibody | >1 publications with TFR and FTH1 |
Pathways associated with anti-TFR antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Clathrin Derived Vesicle Budding Pathway antibodies | Clathrin Derived Vesicle Budding Pathway Diagram |
| Endocytosis Pathway antibodies | Endocytosis Pathway Diagram |
| Endocytosis Pathway antibodies | Endocytosis Pathway Diagram |
| FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies | FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram |
| Golgi Associated Vesicle Biogenesis Pathway antibodies | Golgi Associated Vesicle Biogenesis Pathway Diagram |
| HIF-1 Signaling Pathway antibodies | HIF-1 Signaling Pathway Diagram |
| HIF-1-alpha Transcription Factor Network Pathway antibodies | HIF-1-alpha Transcription Factor Network Pathway Diagram |
| Hematopoietic Cell Lineage Pathway antibodies | Hematopoietic Cell Lineage Pathway Diagram |
| Hematopoietic Cell Lineage Pathway antibodies | Hematopoietic Cell Lineage Pathway Diagram |
| Iron Metabolism In Placenta Pathway antibodies | Iron Metabolism In Placenta Pathway Diagram |
Diseases associated with anti-TFR antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >33 publications with TFR and Neoplasms |
| Iron Metabolism Disorders Antibodies | >28 publications with TFR and Iron Metabolism Disorders |
| Anemia Antibodies | >16 publications with TFR and Anemia |
| Disease Models, Animal Antibodies | >11 publications with TFR and Disease Models, Animal |
| Anemia, Iron-Deficiency Antibodies | >8 publications with TFR and Anemia, Iron-Deficiency |
| Lung Neoplasms Antibodies | >7 publications with TFR and Lung Neoplasms |
| Liver Diseases Antibodies | >6 publications with TFR and Liver Diseases |
| Brain Diseases Antibodies | >5 publications with TFR and Brain Diseases |
| Drug Toxicity Antibodies | >5 publications with TFR and Drug Toxicity |
| Inflammation Antibodies | >5 publications with TFR and Inflammation |
Organs/Tissues associated with anti-TFR antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >35 publications with TFR and Blood |
| Liver Antibodies | >22 publications with TFR and Liver |
| Brain Antibodies | >16 publications with TFR and Brain |
| Intestine Antibodies | >12 publications with TFR and Intestine |
| Lung Antibodies | >10 publications with TFR and Lung |
| Bone Antibodies | >9 publications with TFR and Bone |
| Skin Antibodies | >7 publications with TFR and Skin |
| Kidney Antibodies | >7 publications with TFR and Kidney |
| Embryonic Tissue Antibodies | >6 publications with TFR and Embryonic Tissue |
| Prostate Antibodies | >5 publications with TFR and Prostate |