DLin-MC3-DMA [1224606-06-7]

Cat# orb507413-100mg

Size : 100mg

Brand : Biorbyt

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DLin-MC3-DMA

SKU: orb507413

Description

D-Lin-MC3-DMA(MC3) is the most potent cationic lipid that has been synthesized for Lipid nanoparticles (LNPs) to deliver the siRNA.

Research Area

Immunology & Inflammation

Images & Validation

Application Notes
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

Key Properties

CAS Number1224606-06-7
MW641.61
Purity>98%
FormulaC43H79NO2
SMILESCCCCC/C=C\C/C=C\CCCCCCCCC(OC(=O)CCCN(C)C)CCCCCCCC/C=C\C/C=C\CCCCC

Storage & Handling

StoragePure form: -20°C/3 years,4°C/2 years; In solvent: -20°C/1 month
Expiration Date12 months from date of receipt.
Hazard InformationNon-Toxic
DisclaimerFor research use only

Alternative Names

1224606-06-7, D-Lin-MC3-DMA, (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate
  • 4A3-SCC-PH [orb2703758]

    >95%

    1948.094

    C91H171N3O16S12

    100 mg, 25 mg, 50 mg
  • 119-23 [orb2815799]

    2953044-98-7

    908.47

    C58H105N3O4

    10 mg, 50 mg
  • Dlin-MeOH [orb1983102]

    99.95% (May vary between batches)

    1169768-28-8

    528.94

    C37H68O

    50 mg, 1 ml x 10 mM (in DMSO), 5 mg, 10 mg, 25 mg, 100 mg, 500 mg, 2 mg
  • nor-MC3 [orb3178013]

    50 mg, 10 mg

Key Properties

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Protocol Information

Ye Zeng 1, Mariona Estapé Senti 2, M Clara I Labonia 3, Panagiota Papadopoulou 1, Maike A D Brans 3, Inge Dokter 3 4, Marcel H Fens 5, Alain van Mil 3 4, Joost P G Sluijter 3 4, Raymond M Schiffelers 2, Pieter Vader 2 3, Alexander Kros 1 Fusogenic Coiled-Coil Peptides Enhance Lipid Nanoparticle-Mediated mRNA Delivery upon Intramyocardial Administration ACS Nano, 17(23), 23466–23477 (2023)

Applications

Cell Screening

Reactivity

Human

Gangyin Zhao 1 2, Ye Zeng 3, Wanli Cheng 4, Sofia Karkampouna 4 5, Panagiota Papadopoulou 3, Bochuan Hu 3, Shuya Zang 3, Emma Wezenberg 3, Gabriel Forn-Cuní 1, Bruno Lopes-Bastos 1, Marianna Kruithof-de Julio 5, Alexander Kros 3, B Ewa Snaar-Jagalska 1 Peptide-Modified Lipid Nanoparticles Boost the Antitumor Efficacy of RNA Therapeutics ACS Nano, (2025)

Applications

Cell Screening

Reactivity

Mouse

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