Glutaminase C-IN-1 [311795-38-7]
Cat# T3964-10mg
Size : 10mg
Brand : TargetMol
Contact local distributor :
Phone : +1 850 650 7790
Glutaminase C-IN-1
(Synonyms: Glutaminase Inhibitor Compound 968, Compound 968) Copy Product Info
Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C (GLS1).
Cas No. 311795-38-7
For research use only—not for human use. No sales to individuals. Use as intended only.
Select Batch
Purity:99.91%
Appearance:Solid
Color:White to Yellow
COA LCMS HNMR
Product Introduction
Glutaminase C-IN-1 AI Summary
Glutaminase C-IN-1 exhibits a diverse range of bioactivities, notably functioning as an antagonist for the NFkB signaling pathway with a potency of 667.7 nM. It possesses inhibitory effects on cell proliferation across various cell lines, including hMSC, TMD8, ED40515 IL2 dependent ATL cell lines, and Plasmodium falciparum, with potencies ranging from 525.8 nM to 37221.2 nM. Additionally, it shows sensitization or mitigation effects in immunotoxin studies within the potency range of 11770.4 nM to 37221.2 nM. Furthermore, Glutaminase C-IN-1 inhibits GAC enzyme activity, exhibiting an IC50 value of 9300.0 nM. These findings underscore its potential in multiple therapeutic applications..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C (GLS1). |
| Synonyms | Glutaminase Inhibitor Compound 968, Compound 968 |
| Molecular Weight | 475.42 |
| Formula | C27H27BrN2O |
| Cas No. | 311795-38-7 |
| Smiles | CN(C)c1ccc(cc1Br)C1Nc2ccc3ccccc3c2C2=C1C(=O)CC(C)(C)C2 |
| Relative Density. | 1.39 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (105.17 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Corn Oil: 2.5 mg/mL (5.26 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||