Human Prolactin
Cat# MBS691738-0,05mg
Size : 0.05mg
Brand : MyBiosource
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Prolactin (PRL) Human Active Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691738Prolactin, also known as mammotrophin, luterotropic hormone, and lutetropin, is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an… More details
Product Overview
Online Datasheet in PDFProduct Name
Prolactin (PRL), Active Protein
Full Product Name
Human Prolactin
Product Gene Name
PRL active protein
Product Synonym Names
Recombinant Human Prolactin
Sequence
MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYT HGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR S WNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQ VHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HK IDNYLKLL KCRIIHNNNC
Host
E Coli
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
> 95% by SDS-PAGE and HPLC analysis
Molecular Weight
23 kDa
Chromosome Location
Chromosome: 6; NC_000006.12 (22287244..22302853, complement). Location: 6p22.3
OMIM
176760
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin Level
< 0.1 ng per ug of Prolactin
Biological Activity
Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.
Product Categories/Family for PRL active protein
Cytokines & Growth Factors
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of PRL active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PRL purchase
MBS691738 is an active protein targeting PRL. Also known as Human Prolactin. Reactive in Human. Host: E Coli.
Additional Details
NCBI/Uniprot data below describe general gene information for PRL. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
prolactin
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
PRL
UniProt Protein Name
Prolactin
Protein Family
Prolactin
UniProt Gene Name
PRL
UniProt Synonym Gene Names
PRL
UniProt Entry Name
PRL_HUMAN
NCBI Protein Information
prolactin; decidual prolactin
NCBI Summary for PRL
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
Show more UniProt Comments for PRL
Function: Prolactin acts primarily on the mammary gland by promoting lactation.
Subcellular location: Secreted.
Sequence similarities: Belongs to the somatotropin/prolactin family.
Sequence caution: The sequence CAA38264.1 differs from that shown. Reason: Frameshift at position 8.
Subcellular location: Secreted.
Sequence similarities: Belongs to the somatotropin/prolactin family.
Sequence caution: The sequence CAA38264.1 differs from that shown. Reason: Frameshift at position 8.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with PRL active protein
| Reference Product | PubMed Publications |
|---|---|
| FSH active protein | >2307 publications with PRL and FSH |
| PRLR active protein | >324 publications with PRL and PRLR |
| JAK2 active protein | >179 publications with PRL and JAK2 |
| POU1F1 active protein | >139 publications with PRL and POU1F1 |
| STAT3 active protein | >56 publications with PRL and STAT3 |
| GHR active protein | >52 publications with PRL and GHR |
| ESR1 active protein | >10 publications with PRL and ESR1 |
| PTPN11 active protein | >6 publications with PRL and PTPN11 |
Pathways associated with PRL active protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Amyloids Pathway antibodies | Amyloids Pathway Diagram |
| Cytokine Signaling In Immune System Pathway antibodies | Cytokine Signaling In Immune System Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Disease Pathway antibodies | Disease Pathway Diagram |
| ErbB4 Signaling Events Pathway antibodies | ErbB4 Signaling Events Pathway Diagram |
| Glucocorticoid Receptor Regulatory Network Pathway antibodies | Glucocorticoid Receptor Regulatory Network Pathway Diagram |
| Growth Hormone Receptor Signaling Pathway antibodies | Growth Hormone Receptor Signaling Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Jak-STAT Signaling Pathway antibodies | Jak-STAT Signaling Pathway Diagram |
Diseases associated with PRL active protein
| Disease Name | Pubmed Publications |
|---|---|
| Pituitary Neoplasms Antibodies | >1988 publications with PRL and Pituitary Neoplasms |
| Hyperprolactinemia Antibodies | >1485 publications with PRL and Hyperprolactinemia |
| Adenoma Antibodies | >1460 publications with PRL and Adenoma |
| Prolactinoma Antibodies | >656 publications with PRL and Prolactinoma |
| Mental Disorders Antibodies | >587 publications with PRL and Mental Disorders |
| Amenorrhea Antibodies | >427 publications with PRL and Amenorrhea |
| Galactorrhea Antibodies | >314 publications with PRL and Galactorrhea |
| Growth Hormone-Secreting Pituitary Adenoma Antibodies | >258 publications with PRL and Growth Hormone-Secreting Pituitary Adenoma |
| Infertility, Female Antibodies | >228 publications with PRL and Infertility, Female |
| Hypogonadism Antibodies | >201 publications with PRL and Hypogonadism |
Organs/Tissues associated with PRL active protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Testis Antibodies | >488 publications with PRL and Testis |
| Uncharacterized Tissue Antibodies | >1 publications with PRL and Uncharacterized Tissue |