Human TNF-R1

Cat# 600299

Size : 0.01mg

Brand : Abbiotec

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Recombinant Protein
Cat. No. 
600299
Unit 
0.01 mg
Description 

Two types of soluble TNF receptors (sTNF-R1 and sTNF-R2) have been identified which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women. Recombinant sTNF-R1 comprises a 161 amino acid fragment (41-201) corresponding to the mature TNF-R1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag.