Reagents and instruments for immunology, cell biology and molecular biology.
 
> Integrin alpha 9 beta 1 (Integrin alpha 9, ITGA9, Integrin beta 1, ITGB1, Alpha-RLC, CD29, Fibronectin Receptor Subunit beta, FNRB, GPIIA, Integrin alpha-RLC, ITGA4L, MDF2, MSK12, RLC, VLA-4 Subunit beta, VLA-beta, VLAB) (HRP)

Integrin alpha 9 beta 1 (Integrin alpha 9, ITGA9, Integrin beta 1, ITGB1, Alpha-RLC, CD29, Fibronectin Receptor Subunit beta, FNRB, GPIIA, Integrin alpha-RLC, ITGA4L, MDF2, MSK12, RLC, VLA-4 Subunit beta, VLA-beta, VLAB) (HRP)

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Cat# I7661-36Z7-HRP-100ul

Size : 100ul

Brand : US Biological

Contact local distributor :


Phone : +1 850 650 7790

I7661-36Z7-HRPIntegrin alpha 9 beta 1 (Integrin alpha 9, ITGA9, Integrin beta 1, ITGB1, Alpha-RLC, CD29, Fibronectin Receptor Subunit beta, FNRB, GPIIA, Integrin alpha-RLC, ITGA4L, MDF2, MSK12, RLC, VLA-4 Subunit beta, VLA-beta, VLAB) (HRP)

Specifications
Clone TypeMonoclonal
Hostmouse
Sourcehuman
Swiss ProtQ13797
IsotypeIgG1
GradeAffinity Purified
ApplicationsIP
CrossreactivityGp Hu Po
Shipping TempBlue Ice
Storage Temp-20°C

Alpha9 integrin is a 140kD glycoprotein expressed as a heterodimer in association with the beta1 integrin. The alpha9 integrin is expressed by epithelial cells, including airway epithelial cells.

Applications:
Suitable for use in Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Hybridoma:
SP2/0 myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG1|Clone No: 10D291 (Y9A2)|Host: mouse|Source: human|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).|Purity: Purified by Protein G affinity chromatography from tissue culture supernatant.|Immunogen: Alpha9 integrin transfected lambda cells|Specificity: Recognizes human alpha9 integrin. Inhibits adhesion of alpha9 expressing cells to N-terminal osteopontin. Species crossreactivity: porcine and guinea pig||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Alpha9 integrin transfected lambda cells
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Purity
Purified by Protein G affinity chromatography from tissue culture supernatant.
Specificity
Recognizes human alpha9 integrin. Inhibits adhesion of alpha9 expressing cells to N-terminal osteopontin. Species crossreactivity: porcine and guinea pig
References
1. Wang, A. et al. (1996) Differential regulation of airway epithelial integrins by growth factors. Am. J. Respir, Cell. Mol. Biol. 15: 664-672.2. Smith, L. L. et al. (1996) Osteopontin N-terminal domain contains a cryptic adhesive sequence recognised by alpha9 beta1 integrin. J. Biol. Chem. 271: 28485-28491. 3. Yokosaki, Y. et al. (1996) Differential effects of the integrins alpha9 beta1, alphaV/beta3 and alphaV beta6 on cell proliferative responses to tenascin. J. Biol. Chem. 271: 24144-24150.