KLH Conjugated Thyrotropin Releasing Hormone (TRH)

Cat# MBS2097489-5x5mg

Size : 5x5mg

Brand : MyBiosource

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TRH Small Molecule – Thyrotropin Releasing Hormone

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2097489
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MBS2097489 is a small molecule targeting TRH. Also known as KLH Conjugated Thyrotropin Releasing Hormone (TRH). Reactive in Rat. More details

Product Overview

Product Name
Thyrotropin Releasing Hormone (TRH), Small Molecule
Full Product Name
KLH Conjugated Thyrotropin Releasing Hormone (TRH)
Product Gene Name
TRH small molecule
Product Synonym Names
TRF; Thyrotropin-Releasing Factor; Thyroliberin; Protirelin; Pro-tirelin; Prothyroliberin; TSH-releasing factor
Species Reactivity
Rat
Form/Format
Freeze-dried powder
Purity/Purification
> 95%
Molecular Weight
Predicted Molecular Weight: 380.4Da
3D Structure
ModBase 3D Structure for P01150
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Expression System
Protein conjugation
Tag
N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Product Categories/Family for TRH small molecule

ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for TRH small molecule
Immunogen, SDS-PAGE, Western Blot (WB)

Other Notes

Small volumes of TRH small molecule vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thyrotropin releasing hormone preproprotein
NCBI Official Synonym Full Names
thyrotropin releasing hormone
NCBI Official Symbol
Trh
NCBI Official Synonym Symbols
THR; Trf; TRH01; Pro-TRH
UniProt Protein Name
Pro-thyrotropin-releasing hormone
UniProt Synonym Protein Names
Prothyroliberin
Protein Family
Pro-thyrotropin-releasing hormone
UniProt Gene Name
Trh
UniProt Synonym Gene Names
Pro-TRH; TRH; TRF
NCBI Protein Information
thyrotropin releasing hormone

NCBI Summary for TRH

This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The rat proprotein contains five thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin, and may be involved in cardiac function in heart failure. Disruption of this gene is associated with hypothyroidism, elevated thyroid-stimulating hormone levels, and hyperglycemia. [provided by RefSeq, May 2013]
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UniProt Comments for TRH

Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TRH small molecule

 Products by Pathway  Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with TRH small molecule

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1201 publications with TRH and Neoplasms
 Hypothyroidism Antibodies  >1117 publications with TRH and Hypothyroidism
 Thyroid Neoplasms Antibodies  >314 publications with TRH and Thyroid Neoplasms
 Skin Diseases Antibodies  >187 publications with TRH and Skin Diseases
 Kidney Diseases Antibodies  >146 publications with TRH and Kidney Diseases
 Head and Neck Neoplasms Antibodies  >145 publications with TRH and Head and Neck Neoplasms
 Diabetes Mellitus Antibodies  >143 publications with TRH and Diabetes Mellitus
 Wounds and Injuries Antibodies  >139 publications with TRH and Wounds and Injuries
 Carcinoma Antibodies  >126 publications with TRH and Carcinoma
 Obesity Antibodies  >118 publications with TRH and Obesity

Organs/Tissues associated with TRH small molecule

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4479 publications with TRH and Brain
 Testis Antibodies  >97 publications with TRH and Testis
 Embryonic Tissue Antibodies  >61 publications with TRH and Embryonic Tissue
 Placenta Antibodies  >46 publications with TRH and Placenta
 Spleen Antibodies  >19 publications with TRH and Spleen