LOK Blocking Peptide
Cat# MBS823031-5x5mg
Size : 5x5mg
Brand : MyBiosource
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LOK Blocking Peptide – >85% Purity
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS823031MBS823031 is a blocking peptide targeting STK10. Also known as LOK Blocking Peptide. Reactive in Human. Host: Synthetic. The peptide is used to block Anti-LOK Antibody reactivity. More details
Product Overview
Online Datasheet in PDFProduct Name
LOK (STK10), Blocking Peptide
Full Product Name
LOK Blocking Peptide
Product Gene Name
STK10 blocking peptide
Product Synonym Names
LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase
Host
Synthetic
Species Reactivity
Human
Form/Format
Lyophilized powder
Purity/Purification
>85%
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Antibody/Peptide Pairs
LOK peptide (MBS823031) is used for blocking the activity of LOK antibody (MBS821204)
Molecular Weight
112,135 Da
OMIM
phenotype 603919
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Applications Tested/Suitable for STK10 blocking peptide
Blocking (BL)
Application Notes for STK10 blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Other Notes
Small volumes of STK10 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for STK10. It may not necessarily be applicable to this product.
NCBI Official Full Name
serine/threonine-protein kinase 10
NCBI Official Synonym Full Names
serine/threonine kinase 10
NCBI Official Symbol
STK10
NCBI Official Synonym Symbols
LOK; PRO2729
UniProt Protein Name
Serine/threonine-protein kinase 10
UniProt Synonym Protein Names
Lymphocyte-oriented kinase
Protein Family
Serine/threonine-protein kinase
UniProt Gene Name
STK10
UniProt Synonym Gene Names
LOK
UniProt Entry Name
STK10_HUMAN
NCBI Protein Information
serine/threonine-protein kinase 10; lymphocyte-oriented kinase
NCBI Summary for STK10
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for STK10
LOK: a protein kinase of the STE20 family. Highly expressed in hematopoietic tissue. May cooperate with SLK to regulate Plk1 function in human cells.
Protein type: Kinase, protein; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; STE group; STE20 family; SLK subfamily
Chromosomal Location of Human Ortholog: 5q35.1
Cellular Component: cytoplasm; plasma membrane
Molecular Function: protein serine/threonine kinase activity; identical protein binding; protein binding; protein homodimerization activity; polo kinase kinase activity; ATP binding
Biological Process: protein amino acid autophosphorylation; cell cycle; protein amino acid phosphorylation
Show more Protein type: Kinase, protein; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; STE group; STE20 family; SLK subfamily
Chromosomal Location of Human Ortholog: 5q35.1
Cellular Component: cytoplasm; plasma membrane
Molecular Function: protein serine/threonine kinase activity; identical protein binding; protein binding; protein homodimerization activity; polo kinase kinase activity; ATP binding
Biological Process: protein amino acid autophosphorylation; cell cycle; protein amino acid phosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Diseases associated with STK10 blocking peptide
| Disease Name | Pubmed Publications |
|---|---|
| Drug-Related Side Effects and Adverse Reactions Antibodies | >1 publications with STK10 and Drug-Related Side Effects and Adverse Reactions |
| Disease Models, Animal Antibodies | >1 publications with STK10 and Disease Models, Animal |
| Inflammation Antibodies | >1 publications with STK10 and Inflammation |
Organs/Tissues associated with STK10 blocking peptide
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >6 publications with STK10 and Blood |
| Muscle Antibodies | >1 publications with STK10 and Muscle |
| Lymph Node Antibodies | >1 publications with STK10 and Lymph Node |
| Pancreas Antibodies | >1 publications with STK10 and Pancreas |
| Bone Antibodies | >1 publications with STK10 and Bone |
| Thymus Antibodies | >1 publications with STK10 and Thymus |
| Spleen Antibodies | >1 publications with STK10 and Spleen |
| Skin Antibodies | >1 publications with STK10 and Skin |
| Bone Marrow Antibodies | >1 publications with STK10 and Bone Marrow |
| Uncharacterized Tissue Antibodies | >1 publications with STK10 and Uncharacterized Tissue |