Maltotetraose

Cat# 297384-10mg

Size : 10mg

Brand : US Biological

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297384 Maltotetraose

Grade
Highly Purified
Shipping Temp
RT
Storage Temp
4°C

Maltotetraose is a tetrasaccharide that is composed of glucose molecules linked by α-1,4 glycosidic bonds and has been found in B. stearothermophilus.1,2,3,4 It increases the α-amylase synthesis rate in B. stearothermophilus 3-fold greater than sucrose or glucose when used at a concentration of 0.1mM.2 Maltotetraose (750ug/ml) inhibits the growth of E. carotovora in a cylinder-agar plate assay but does not affect the growth of several other microorganisms.4 It also inhibits TNF-α-induced expression of intercellular adhesion molecule-1 (ICAM-1) in MOVAS-1 mouse smooth muscle cells (VSMCs) transfected with an ICAM-1 luciferase reporter when used at a concentration of 20uM.5

Synonyms:
O-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-D-Glucose; Amylotetraose; α-1,4-Tetraglucose

CAS No:
34612-38-9

Molecular Formula:
C₂₄H₄₂O₂₁

Molecular Weight:
666.58

Appearance:
White to off-white powder

Purity:
≥95%

Melting Point:
209-211°C (dec.)

Solubility:
Methanol (Very Slightly, Heated), Water (Slightly)

Storage:
4°C

Applications
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. ||Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Form
White to off-white powder
Purity
≥95%
References
1. Sauer, J., Sigurskjold, B.W., Christensen, U., et al. Glucoamylase: Structure/function relationships, and protein engineering Biochim. Biophys. Acta. 1543(2), 275-293 (2000).|2. Welker, N.E., and Campbell, L.L. Induction of α-amylase of Bacillus stearothermophilus by maltodextrins J. Bacteriol. 86(4), 687-691 (1963).|3. Fujita, M., Torigoe, K., Nakada, T., et al. Cloning and nucleotide sequence of the gene (amyP) for maltotetraose-forming amylase from Pseudomonas stutzeri MO-19 J. Bacteriol. 171(3), 1333-1339 (1989).|4. Kondo, H., Honke, T., Hasegawa, R., et al. Isolation of maltotetraose from Streptomyces as an antibiotic against Erwinia carotovora J. Antibiot. (Tokyo) 28(2), 157-160 (1975).|5. Shin, S.Y., Jung, Y.J., Yong, Y., et al. Inhibition of PDGF-induced migration and TNF-α-induced ICAM-1 expression by maltotetraose from bamboo stem extract (BSE) in mouse vascular smooth muscle cells Mol. Nutr. Food Res. 60(9), 2086-2097 (2016).|5. Ezure, Y. et al.: Biosci. Biotech. Biochem., 61, 1931 (1997)|6. Hatonen, K. et al.: Am. J. Clin. Nutr., 96, 44 (2012)