Mouse PAI-1 genetically deficient plasma, sodium citrate
Cat# MBS135594-0,05mL
Size : 0.05mL
Brand : MyBiosource
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SERPINE1 Plasma – PAI-1 Genetically Deficient Plasma, Sodium Citrate
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS135594This plasma is an ideal negative control for ELISA based assays and other experiments involving PAI-1. Collected from homozygous PAI-1 knockout mice of strain B6.129S2-Serpine1 tm1Mlg /J. Anticoagulated with sodium citrate and flash frozen. Collected from More details
Product Overview
Online Datasheet in PDFProduct Name
PAI-1 genetically deficient plasma, sodium citrate (SERPINE1), Plasma
Full Product Name
Mouse PAI-1 genetically deficient plasma, sodium citrate
Product Gene Name
SERPINE1 plasma
Host
PAI-1 knockout mouse
Form/Format
Frozen liquid
Purity/Purification
Organ
Preparation and Storage
Store at -70 degree C. Shelf Life: 3 years from delivery
Other Notes
Small volumes of SERPINE1 plasma vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for SERPINE1 purchase
MBS135594 is a plasma targeting SERPINE1. Also known as Mouse PAI-1 genetically deficient plasma, sodium citrate. Host: PAI-1 knockout mouse.
Additional Details
NCBI/Uniprot data below describe general gene information for SERPINE1. It may not necessarily be applicable to this product.
NCBI Official Full Name
Plasminogen activator inhibitor 1
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade E, member 1
NCBI Official Symbol
Serpine1
NCBI Official Synonym Symbols
PAI1; PAI-1; Planh1
UniProt Protein Name
Plasminogen activator inhibitor 1
UniProt Synonym Protein Names
Endothelial plasminogen activator inhibitor; Serpin E1
Protein Family
Plasminogen activator inhibitor
UniProt Gene Name
Serpine1
UniProt Synonym Gene Names
Mr1; Pai1; Planh1; PAI; PAI-1
UniProt Entry Name
PAI1_MOUSE
NCBI Protein Information
plasminogen activator inhibitor 1; PAI; serpin E1; plasminogen activator inhibitor, type I; endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI)
UniProt Comments for SERPINE1
SERPINE1: a secreted protein that acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Belongs to the serpin family. Interacts with VTN. Binds LRP1B; binding is followed by internalization and degradation. Plasma levels of PAI-1 and VCAM-1 together may be useful in predicting post-operative recurrence in patients with colorectal cancer.
Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis
Cellular Component: extracellular matrix; extracellular space; extracellular region
Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protease binding; protease inhibitor activity; receptor binding
Biological Process: positive regulation of keratinocyte migration; positive regulation of blood coagulation; wound healing; negative regulation of peptidase activity; positive regulation of coagulation; negative regulation of smooth muscle cell migration; defense response to Gram-negative bacterium; regulation of angiogenesis; positive regulation of receptor-mediated endocytosis; regulation of cell proliferation; positive regulation of interleukin-8 production; positive regulation of angiogenesis; positive regulation of fibroblast proliferation; negative regulation of fibrinolysis; regulation of receptor activity; negative regulation of cell migration; negative regulation of cell adhesion mediated by integrin; female gonad development; positive regulation of inflammatory response
Show more Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis
Cellular Component: extracellular matrix; extracellular space; extracellular region
Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protease binding; protease inhibitor activity; receptor binding
Biological Process: positive regulation of keratinocyte migration; positive regulation of blood coagulation; wound healing; negative regulation of peptidase activity; positive regulation of coagulation; negative regulation of smooth muscle cell migration; defense response to Gram-negative bacterium; regulation of angiogenesis; positive regulation of receptor-mediated endocytosis; regulation of cell proliferation; positive regulation of interleukin-8 production; positive regulation of angiogenesis; positive regulation of fibroblast proliferation; negative regulation of fibrinolysis; regulation of receptor activity; negative regulation of cell migration; negative regulation of cell adhesion mediated by integrin; female gonad development; positive regulation of inflammatory response
Research Articles on SERPINE1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with SERPINE1 plasma
| Products by Pathway | Pathway Diagram |
|---|---|
| Adipogenesis Pathway antibodies | Adipogenesis Pathway Diagram |
| BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway antibodies | BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway Diagram |
| Blood Clotting Cascade Pathway antibodies | Blood Clotting Cascade Pathway Diagram |
| Chagas Disease (American Trypanosomiasis) Pathway antibodies | Chagas Disease (American Trypanosomiasis) Pathway Diagram |
| Chagas Disease (American Trypanosomiasis) Pathway antibodies | Chagas Disease (American Trypanosomiasis) Pathway Diagram |
| Circadian Clock Pathway antibodies | Circadian Clock Pathway Diagram |
| Complement And Coagulation Cascades Pathway antibodies | Complement And Coagulation Cascades Pathway Diagram |
| Complement And Coagulation Cascades Pathway antibodies | Complement And Coagulation Cascades Pathway Diagram |
| Complement And Coagulation Cascades Pathway antibodies | Complement And Coagulation Cascades Pathway Diagram |
| Dissolution Of Fibrin Clot Pathway antibodies | Dissolution Of Fibrin Clot Pathway Diagram |
Organs/Tissues associated with SERPINE1 plasma
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Connective Tissue Antibodies | >539 publications with SERPINE1 and Connective Tissue |
| Lung Antibodies | >511 publications with SERPINE1 and Lung |
| Embryonic Tissue Antibodies | >321 publications with SERPINE1 and Embryonic Tissue |
| Bone Marrow Antibodies | >98 publications with SERPINE1 and Bone Marrow |
| Eye Antibodies | >92 publications with SERPINE1 and Eye |
| Joint Antibodies | >88 publications with SERPINE1 and Joint |
| Spleen Antibodies | >22 publications with SERPINE1 and Spleen |
| Testis Antibodies | >21 publications with SERPINE1 and Testis |
| Mammary Gland Antibodies | >19 publications with SERPINE1 and Mammary Gland |
| Thymus Antibodies | >3 publications with SERPINE1 and Thymus |