PEPC (Phospho-Ser15) Polyclonal Antibody
Cat# MBS8585388-0,1mL-Biotin
Size : 0.1mL(Biotin)
Brand : MyBiosource
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PEPC Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8585388MBS8585388 is an antibody targeting PEPC. Also known as PEPC (Phospho-Ser15) Polyclonal Antibody. Reactive in Plant. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
PEPC, Polyclonal Antibody
Full Product Name
PEPC (Phospho-Ser15) Polyclonal Antibody
Product Gene Name
anti-PEPC antibody
Product Synonym Names
PGC; Gastricsin; Pepsinogen C
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Plant
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purity/Purification
The antibody was affinity-purified from antiserum by affinity-chromatography
Specificity
The antibody detects endogenous PEPC (Phospho Ser15) protein.
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
Applications Tested/Suitable for anti-PEPC antibody
Western Blot (WB)
Application Notes for anti-PEPC antibody
WB: 1:1000-2000
Other Notes
Small volumes of anti-PEPC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for PEPC. It may not necessarily be applicable to this product.
NCBI Official Full Name
Gastricsin
NCBI Official Synonym Full Names
progastricsin (pepsinogen C)
NCBI Official Symbol
PGC
NCBI Official Synonym Symbols
PEPC; PGII
UniProt Protein Name
Gastricsin
UniProt Synonym Protein Names
Pepsinogen C
Protein Family
Aminopeptidase
UniProt Gene Name
PGC
UniProt Entry Name
PEPC_HUMAN
NCBI Protein Information
gastricsin; pepsin C; pepsinogen C; preprogastricsin; pepsinogen group II
NCBI Summary for PEPC
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Show more UniProt Comments for PEPC
PGC: Hydrolyzes a variety of proteins. Belongs to the peptidase A1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Protease; Secreted; EC 3.4.23.3
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: extracellular space
Molecular Function: aspartic-type endopeptidase activity
Biological Process: digestion; proteolysis
Show more Protein type: Secreted, signal peptide; Protease; Secreted; EC 3.4.23.3
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: extracellular space
Molecular Function: aspartic-type endopeptidase activity
Biological Process: digestion; proteolysis
Research Articles on PEPC
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-PEPC antibody
| Reference Product | PubMed Publications |
|---|---|
| PGD antibody | >9 publications with PEPC and PGD |
| PCK1 antibody | >8 publications with PEPC and PCK1 |
| ESR1 antibody | >1 publications with PEPC and ESR1 |
| PCK2 antibody | >1 publications with PEPC and PCK2 |
Diseases associated with anti-PEPC antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >265 publications with PEPC and Nervous System Diseases |
| Cardiovascular Diseases Antibodies | >251 publications with PEPC and Cardiovascular Diseases |
| Disease Models, Animal Antibodies | >236 publications with PEPC and Disease Models, Animal |
| Inflammation Antibodies | >200 publications with PEPC and Inflammation |
| Fatty Liver Antibodies | >185 publications with PEPC and Fatty Liver |
| Liver Diseases Antibodies | >147 publications with PEPC and Liver Diseases |
| Heart Diseases Antibodies | >144 publications with PEPC and Heart Diseases |
| Hypertrophy Antibodies | >112 publications with PEPC and Hypertrophy |
| Necrosis Antibodies | >107 publications with PEPC and Necrosis |
| Atrophy Antibodies | >106 publications with PEPC and Atrophy |
Organs/Tissues associated with anti-PEPC antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Liver Antibodies | >524 publications with PEPC and Liver |
| Heart Antibodies | >354 publications with PEPC and Heart |
| Brain Antibodies | >287 publications with PEPC and Brain |
| Connective Tissue Antibodies | >223 publications with PEPC and Connective Tissue |
| Stomach Antibodies | >83 publications with PEPC and Stomach |
| Pancreas Antibodies | >54 publications with PEPC and Pancreas |
| Lung Antibodies | >44 publications with PEPC and Lung |
| Prostate Antibodies | >15 publications with PEPC and Prostate |
| Esophagus Antibodies | >4 publications with PEPC and Esophagus |
| Uncharacterized Tissue Antibodies | >1 publications with PEPC and Uncharacterized Tissue |