PIEZO1 Polyclonal Antibody
Cat# MBS2548162-0,06mL
Size : 0.06mL
Brand : MyBiosource
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Phone : +1 850 650 7790
Western Blot analysis of extracts of various cells lines with PIEZO1 Polyclonal antibody
PIEZO1 Antibody – Rabbit
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2548162The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with… More details
Product Overview
Online Datasheet in PDFProduct Name
PIEZO1, Antibody
Full Product Name
PIEZO1 Polyclonal Antibody
Product Gene Name
anti-PIEZO1 antibody
Product Synonym Names
DHS; FAM38A; LMPH3; Mib
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
Calculated MW: 286kDa
Observed MW: 300kDa
Observed MW: 300kDa
OMIM
AC138028 Genomic DNA
Immunogen
Recombinant protein of human PIEZO1
Note
Centrifuge before opening to ensure complete recovery of vial contents.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PIEZO1 antibody
Western Blot (WB)
Application Notes for anti-PIEZO1 antibody
WB: 1:500 - 1:2000
Other Notes
Small volumes of anti-PIEZO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PIEZO1 purchase
MBS2548162 is an antibody targeting PIEZO1. Also known as PIEZO1 Polyclonal Antibody. Reactive in Human. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for PIEZO1. It may not necessarily be applicable to this product.
NCBI Official Full Name
piezo-type mechanosensitive ion channel component 1
NCBI Official Synonym Full Names
piezo type mechanosensitive ion channel component 1
NCBI Official Symbol
PIEZO1
NCBI Official Synonym Symbols
DHS; Mib; LMPH3; FAM38A
UniProt Protein Name
Piezo-type mechanosensitive ion channel component 1
UniProt Synonym Protein Names
Membrane protein induced by beta-amyloid treatment; Mib; Protein FAM38A
Protein Family
Piezo-type mechanosensitive ion channel component
UniProt Gene Name
PIEZO1
UniProt Synonym Gene Names
FAM38A; KIAA0233; Mib
NCBI Protein Information
piezo-type mechanosensitive ion channel component 1
UniProt Comments for PIEZO1
PIEZO1: Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling. Belongs to the PIEZO family.
Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16q24.3
Cellular Component: endoplasmic reticulum; plasma membrane
Molecular Function: cation channel activity; mechanically-gated ion channel activity
Biological Process: cation transport; detection of mechanical stimulus; positive regulation of cell-cell adhesion mediated by integrin; positive regulation of integrin activation; regulation of membrane potential
Disease: Dehydrated Hereditary Stomatocytosis With Or Without Pseudohyperkalemia And/or Perinatal Edema; Lymphedema, Hereditary, Iii
Show more Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16q24.3
Cellular Component: endoplasmic reticulum; plasma membrane
Molecular Function: cation channel activity; mechanically-gated ion channel activity
Biological Process: cation transport; detection of mechanical stimulus; positive regulation of cell-cell adhesion mediated by integrin; positive regulation of integrin activation; regulation of membrane potential
Disease: Dehydrated Hereditary Stomatocytosis With Or Without Pseudohyperkalemia And/or Perinatal Edema; Lymphedema, Hereditary, Iii
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-PIEZO1 antibody
| Reference Product | PubMed Publications |
|---|---|
| SACS antibody | >3 publications with PIEZO1 and SACS |
| RHAG antibody | >2 publications with PIEZO1 and RHAG |
Diseases associated with anti-PIEZO1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Pregnancy Complications Antibodies | >16 publications with PIEZO1 and Pregnancy Complications |
| Nervous System Diseases Antibodies | >3 publications with PIEZO1 and Nervous System Diseases |
| Inflammation Antibodies | >2 publications with PIEZO1 and Inflammation |
| Mental Disorders Antibodies | >1 publications with PIEZO1 and Mental Disorders |
| Hypertrophy Antibodies | >1 publications with PIEZO1 and Hypertrophy |
| Breast Neoplasms Antibodies | >1 publications with PIEZO1 and Breast Neoplasms |
| Necrosis Antibodies | >1 publications with PIEZO1 and Necrosis |
Organs/Tissues associated with anti-PIEZO1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >27 publications with PIEZO1 and Blood |
| Vascular Antibodies | >9 publications with PIEZO1 and Vascular |
| Brain Antibodies | >9 publications with PIEZO1 and Brain |
| Heart Antibodies | >7 publications with PIEZO1 and Heart |
| Muscle Antibodies | >6 publications with PIEZO1 and Muscle |
| Bone Antibodies | >3 publications with PIEZO1 and Bone |
| Bladder Antibodies | >3 publications with PIEZO1 and Bladder |
| Eye Antibodies | >2 publications with PIEZO1 and Eye |
| Skin Antibodies | >2 publications with PIEZO1 and Skin |
| Lung Antibodies | >2 publications with PIEZO1 and Lung |
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