PTPRC Antibody
Cat# OAEE00879
Size : 0.1mg(C100)
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for PTPRC Antibody |
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| Predicted Species Reactivity | Mouse |
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| Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | EM-05 |
| Isotype | IgG |
| Host | Rat |
| Conjugation | PerCP |
| Application | FC |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Murine peripheral blood leukocytes |
| Purification | Purified by size-exclusion chromatography |
| Concentration | 0.5 mg/ml |
| Specificity | The antibody EM-05 reacts with mouse CD45 antigen (Leukocyte Common Antigen), a single chain type I transmembrane protein expressed at high level on cells of hematopoietic origin, except erythrocytes and platelets. |
| Formulation | PerCP |
| Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Reference | Townsend KP, Vendrame M, Ehrhart J, Faza B, Zeng J, Town T, Tan J: CD45 isoform RB as a molecular target to oppose lipopolysaccharide-induced microglial activation in mice. Neurosci Lett. 2004 May 13;362(1):26-30. Dawes R, Petrova S, Liu Z, Wraith D, Beverley PC, Tchilian EZ. Combinations of CD45 isoforms are crucial for immune function and disease. J Immunol. 2006 Mar 15;176(6):3417-25. Byth KF, Conroy LA, Howlett S, Smith AJ, May J, Alexander DR, Holmes N: CD45-null transgenic mice reveal a positive regulatory role for CD45 in earlythymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation. J Exp Med. 1996 Apr 1;183(4):1707-18. Desharnais P, Dupéré-Minier G, Hamelin C, Devine P, Bernier J: Involvement of CD45 in DNA fragmentation in apoptosis induced by mitochondrial perturbing agents. Apoptosis. 2007 Dec 19. |
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| Gene Symbol | Ptprc |
| Gene Full Name | protein tyrosine phosphatase, receptor type, C |
| Alias Symbols | B220, Cd45, CD45R, L-CA, leukocyte common antigen, loc, Ly-, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-, Lyt-4, receptor-type tyrosine-protein phosphatase C, T200. |
| NCBI Gene Id | 19264 |
| Protein Name | protein-tyrosine-phosphatase |
| Uniprot ID | P08575 |
| Protein Accession # | NP_002829.3; NP_563578.2 |
| Nucleotide Accession # | NM_002838.4; NM_080921.3 |
